Monitoring opioid analgesic misuse, abuse and dependence: What to the data from addictovigilance tell us about the situation in France?

IF 2.2 4区 医学 Q3 PHARMACOLOGY & PHARMACY
Maryse Lapeyre-Mestre, Celian Bertin, Constança Jalles, Thomas Soeiro, Joëlle Micallef, Anne Roussin
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引用次数: 0

Abstract

The opioid epidemic has emerged in the USA in the late 1990s and widespread to Canada, Australia, and the UK to a lesser extent in the more recent years. At the European level, several studies performed in different European countries have highlighted that prescription opioid use increased substantially over the last decade, and several proxies for misuse show a parallel increasing trend. The French addictovigilance experience on opioid analgesics is a good example of a specific dedicated monitoring, taking into account in a global and multisource perspective, patterns of utilization, population involved in problematic use, ways of acquisition and health complications. The added value of this data triangulation is illustrated by the recent data on tramadol and oxycodone. The addictovigilance monitoring is particularly relevant to identify early signals of potential problematic use and to assess the impact of campaigns for opioid analgesics rational use and regulatory changes.

监测阿片类镇痛药的误用、滥用和依赖:来自成瘾警惕性的数据告诉我们法国的情况是什么?
阿片类药物流行于20世纪90年代末在美国出现,近年来在较小程度上蔓延到加拿大、澳大利亚和英国。在欧洲一级,在不同欧洲国家进行的几项研究强调,处方阿片类药物的使用在过去十年中大幅增加,滥用的几个替代指标显示出平行增加的趋势。法国在阿片类镇痛药成瘾警戒方面的经验是一个很好的例子,从全球和多来源的角度考虑到具体的专门监测、使用模式、涉及问题使用的人口、获取方式和健康并发症。最近关于曲马多和羟考酮的数据说明了这种数据三角化的附加价值。成瘾警惕性监测对于识别潜在问题使用的早期信号以及评估阿片类镇痛药合理使用和监管变化运动的影响尤其相关。
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来源期刊
Therapie
Therapie 医学-药学
CiteScore
3.50
自引率
7.70%
发文量
132
审稿时长
57 days
期刊介绍: Thérapie is a peer-reviewed journal devoted to Clinical Pharmacology, Therapeutics, Pharmacokinetics, Pharmacovigilance, Addictovigilance, Social Pharmacology, Pharmacoepidemiology, Pharmacoeconomics and Evidence-Based-Medicine. Thérapie publishes in French or in English original articles, general reviews, letters to the editor reporting original findings, correspondence relating to articles or letters published in the Journal, short articles, editorials on up-to-date topics, Pharmacovigilance or Addictovigilance reports that follow the French "guidelines" concerning good practice in pharmacovigilance publications. The journal also publishes thematic issues on topical subject. The journal is indexed in the main international data bases and notably in: Biosis Previews/Biological Abstracts, Embase/Excerpta Medica, Medline/Index Medicus, Science Citation Index.
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