Advances and applications of dynamic surface-enhanced Raman spectroscopy (SERS) for single molecule studies

IF 5.8 3区 材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Nanoscale Pub Date : 2024-12-23 DOI:10.1039/D4NR04239E
Yanqiu Zou, Huaizhou Jin, Qifei Ma, Zhenrong Zheng, Shukun Weng, Karol Kolataj, Guillermo Acuna, Ilko Bald and Denis Garoli
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引用次数: 0

Abstract

Dynamic surface-enhanced Raman spectroscopy (SERS) is nowadays one of the most interesting applications of SERS, in particular for single molecule studies. In fact, it enables the study of real-time processes at the molecular level. This review summarizes the latest developments in dynamic SERS techniques and their applications, focusing on new instrumentation, data analysis methods, temporal resolution and sensitivity improvements, and novel substrates. We highlight the progress and applications of single-molecule dynamic SERS in monitoring chemical reactions, catalysis, biomolecular interactions, conformational dynamics, and real-time sensing and detection. We aim to provide a comprehensive review on its advancements, applications as well as its current challenges and development frontiers.

Abstract Image

动态表面增强拉曼光谱(SERS)在单分子研究中的进展与应用
动态表面增强拉曼光谱(SERS)是目前最有趣的SERS应用之一,特别是在单分子研究中。事实上,它可以在分子水平上研究实时过程。本文综述了动态SERS技术及其应用的最新进展,重点介绍了新的仪器、数据分析方法、时间分辨率和灵敏度的改进以及新的衬底。重点介绍了单分子动态SERS在化学反应监测、催化、生物分子相互作用、构象动力学、实时传感和检测等方面的研究进展和应用。我们的目标是对其进展、应用以及当前的挑战和发展前沿进行全面的综述。
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来源期刊
Nanoscale
Nanoscale CHEMISTRY, MULTIDISCIPLINARY-NANOSCIENCE & NANOTECHNOLOGY
CiteScore
12.10
自引率
3.00%
发文量
1628
审稿时长
1.6 months
期刊介绍: Nanoscale is a high-impact international journal, publishing high-quality research across nanoscience and nanotechnology. Nanoscale publishes a full mix of research articles on experimental and theoretical work, including reviews, communications, and full papers.Highly interdisciplinary, this journal appeals to scientists, researchers and professionals interested in nanoscience and nanotechnology, quantum materials and quantum technology, including the areas of physics, chemistry, biology, medicine, materials, energy/environment, information technology, detection science, healthcare and drug discovery, and electronics.
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