Cover Feature: Phosphate-Containing Glycolipids: A Review on Synthesis and Bioactivity (ChemMedChem 24/2024)

IF 3.6 4区医学 Q2 CHEMISTRY, MEDICINAL

ChemMedChem Pub Date : 2024-12-16 DOI:10.1002/cmdc.202482402

Luís Pinheiro, Marisa Freitas, Paula S. Branco

引用次数: 0

Abstract

Phosphate-containing Glycolipids are structures that are not as widely understood as glycolipids. They are divided into two classes: phosphoglycolipids and glycophospholipids – depending on the position of the phosphate. They are inspired by natural sources of various origins. Because of their lipidic portion they are often associated with biological membranes. Their bioactivities concern mainly anti-metastasis, platelet aggregation, inflammatory, antifungal, antibiotic and neurogenic activities. More details can be found in article 10.1002/cmdc.202400315 by Luís Pinheiro and co-workers.

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封面专题：含磷酸盐糖脂：合成与生物活性综述（ChemMedChem 24/2024）

含磷酸盐的糖脂是一种不像糖脂那样被广泛理解的结构。根据磷酸的位置，它们被分为两类：磷酸糖脂和糖磷脂。他们的灵感来自于各种各样的自然资源。由于它们的脂质部分，它们通常与生物膜有关。其生物活性主要涉及抗转移、血小板聚集、炎症、抗真菌、抗生素和神经源性活性。更多细节可以在10.1002/cmdc中找到。202400315由Luís Pinheiro和同事。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ChemMedChem 医学-药学

CiteScore

6.70

自引率

2.90%

发文量

280

审稿时长

1 months

期刊介绍： Quality research. Outstanding publications. With an impact factor of 3.124 (2019), ChemMedChem is a top journal for research at the interface of chemistry, biology and medicine. It is published on behalf of Chemistry Europe, an association of 16 European chemical societies. ChemMedChem publishes primary as well as critical secondary and tertiary information from authors across and for the world. Its mission is to integrate the wide and flourishing field of medicinal and pharmaceutical sciences, ranging from drug design and discovery to drug development and delivery, from molecular modeling to combinatorial chemistry, from target validation to lead generation and ADMET studies. ChemMedChem typically covers topics on small molecules, therapeutic macromolecules, peptides, peptidomimetics, and aptamers, protein-drug conjugates, nucleic acid therapies, and beginning 2017, nanomedicine, particularly 1) targeted nanodelivery, 2) theranostic nanoparticles, and 3) nanodrugs. Contents ChemMedChem publishes an attractive mixture of: Full Papers and Communications Reviews and Minireviews Patent Reviews Highlights and Concepts Book and Multimedia Reviews.