Primary anorectal mammary-like adenocarcinoma: a potential diagnostic pitfall with conventional colorectal adenocarcinoma.

IF 2.4 3区医学 Q2 PATHOLOGY

Diagnostic Pathology Pub Date : 2024-12-18 DOI:10.1186/s13000-024-01572-4

Margaret L Axelrod, Xiuli Liu, Pooja Navale

引用次数: 0

Abstract

Anogenital mammary-like glands (AGMLGs) are present in the anogenital region that bear striking morphologic and protein-expression similarities to mammary glands in the breast. AGMLGs can give rise to both benign and malignant lesions which mimic primary breast lesions. Herein, we report two mammary-type adenocarcinomas arising from AGMLGs, including one in the previously unreported site of the rectum. Recognition of mammary-type adenocarcinoma in the rectal and anogenital regions is crucial as clinical management options may differ compared to conventional colorectal adenocarcinomas.

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原发性肛肠乳腺样腺癌：与常规结直肠腺癌的潜在诊断缺陷。

肛门生殖器乳腺样腺（AGMLGs）存在于肛门生殖器区域，其形态和蛋白质表达与乳腺中的乳腺相似。AGMLGs可引起良性和恶性病变，类似于原发性乳腺病变。在此，我们报告了两例由AGMLGs引起的乳腺型腺癌，其中一例发生在以前未报道的直肠部位。与传统的结直肠腺癌相比，识别直肠和肛门生殖器区域的乳腺型腺癌是至关重要的，因为临床治疗选择可能不同。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Diagnostic Pathology 医学-病理学

CiteScore

4.60

自引率

0.00%

发文量

审稿时长

1 months

期刊介绍： Diagnostic Pathology is an open access, peer-reviewed, online journal that considers research in surgical and clinical pathology, immunology, and biology, with a special focus on cutting-edge approaches in diagnostic pathology and tissue-based therapy. The journal covers all aspects of surgical pathology, including classic diagnostic pathology, prognosis-related diagnosis (tumor stages, prognosis markers, such as MIB-percentage, hormone receptors, etc.), and therapy-related findings. The journal also focuses on the technological aspects of pathology, including molecular biology techniques, morphometry aspects (stereology, DNA analysis, syntactic structure analysis), communication aspects (telecommunication, virtual microscopy, virtual pathology institutions, etc.), and electronic education and quality assurance (for example interactive publication, on-line references with automated updating, etc.).