Role of Vitamin B in Healthy Ageing and Disease.

Q1 Biochemistry, Genetics and Molecular Biology
Kathleen Mikkelsen, Maria Trapali, Vasso Apostolopoulos
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引用次数: 0

Abstract

B vitamin complex consist of vitamins B1, B2, B5, B6, B9, B12 and is pivotal for overall health, influencing vital functions such as, energy metabolism, DNA maintenance, and healthy immune system. Inadequate B vitamin levels are associated with various health issues, including neurocognitive problems, immune imbalances, and inflammation. In ageing individuals, deficiencies in B vitamins increase the risk of cardiovascular ailments, stroke, cognitive disorders, neurodegeneration, mental health issues, and methylation-related disorders. These result primarily due to changes in glycation, mitochondria, and oxidative stress. Thus, ensuring optimal vitamin B levels in the ageing population may be beneficial in preventing such age-related diseases. In this chapter we discuss the extensive role of B vitamins in the ageing process.

维生素B在健康衰老和疾病中的作用。
B族维生素复合物由维生素B1, B2, B5, B6, B9, B12组成,对整体健康至关重要,影响重要功能,如能量代谢,DNA维护和健康的免疫系统。B族维生素水平不足与各种健康问题有关,包括神经认知问题、免疫失衡和炎症。在老年人中,缺乏B族维生素会增加患心血管疾病、中风、认知障碍、神经退行性疾病、精神健康问题和甲基化相关疾病的风险。这些结果主要是由于糖基化、线粒体和氧化应激的变化。因此,确保老年人口的最佳维生素B水平可能有助于预防此类与年龄有关的疾病。在本章中,我们将讨论B族维生素在衰老过程中的广泛作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Sub-cellular biochemistry
Sub-cellular biochemistry Biochemistry, Genetics and Molecular Biology-Biochemistry
CiteScore
5.90
自引率
0.00%
发文量
33
期刊介绍: The book series SUBCELLULAR BIOCHEMISTRY is a renowned and well recognized forum for disseminating advances of emerging topics in Cell Biology and related subjects. All volumes are edited by established scientists and the individual chapters are written by experts on the relevant topic. The individual chapters of each volume are fully citable and indexed in Medline/Pubmed to ensure maximum visibility of the work.
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