D. S. Shlykova, M. S. Yurkova, A. V. Lipkin, A. N. Fedorov
{"title":"Passive Oral Immunization as a Promising Tool for Treating Rotavirus Infections in Newborns","authors":"D. S. Shlykova, M. S. Yurkova, A. V. Lipkin, A. N. Fedorov","doi":"10.1134/S0003683824605079","DOIUrl":null,"url":null,"abstract":"<p>The development of antiviral drugs due to the high risk of rotavirus infections, especially for newborns, has attracted a lot of attention. This review is devoted to consideration of additional and promising tools for controlling human rotavirus infection (HRI) in newborns—passive oral immunization. Vaccination of animals allows us to obtain immunoglobulins in the form of colostrum and use them against human diseases. The use of bovine colostrum as an additional therapeutic agent against HRI in newborns is analyzed.</p>","PeriodicalId":466,"journal":{"name":"Applied Biochemistry and Microbiology","volume":"60 6","pages":"1087 - 1095"},"PeriodicalIF":1.0000,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Applied Biochemistry and Microbiology","FirstCategoryId":"99","ListUrlMain":"https://link.springer.com/article/10.1134/S0003683824605079","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"BIOTECHNOLOGY & APPLIED MICROBIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
The development of antiviral drugs due to the high risk of rotavirus infections, especially for newborns, has attracted a lot of attention. This review is devoted to consideration of additional and promising tools for controlling human rotavirus infection (HRI) in newborns—passive oral immunization. Vaccination of animals allows us to obtain immunoglobulins in the form of colostrum and use them against human diseases. The use of bovine colostrum as an additional therapeutic agent against HRI in newborns is analyzed.
期刊介绍:
Applied Biochemistry and Microbiology is an international peer reviewed journal that publishes original articles on biochemistry and microbiology that have or may have practical applications. The studies include: enzymes and mechanisms of enzymatic reactions, biosynthesis of low and high molecular physiologically active compounds; the studies of their structure and properties; biogenesis and pathways of their regulation; metabolism of producers of biologically active compounds, biocatalysis in organic synthesis, applied genetics of microorganisms, applied enzymology; protein and metabolic engineering, biochemical bases of phytoimmunity, applied aspects of biochemical and immunochemical analysis; biodegradation of xenobiotics; biosensors; biomedical research (without clinical studies). Along with experimental works, the journal publishes descriptions of novel research techniques and reviews on selected topics.