Synthesis of Pyrrolo[1,2-a]quinoxalines via an Electrochemical C(sp3)-H Functionalization

IF 4.6 1区化学 Q1 CHEMISTRY, ORGANIC

Organic Chemistry Frontiers Pub Date : 2024-12-17 DOI:10.1039/d4qo01981d

Sijie Peng, Tong Li, Kai Li, Qi Sun, Zhiyong Wang

引用次数: 0

Abstract

An efficient iodine-mediated electrochemical C(sp3)-H cyclization was developed under mild conditions. A variety of functionalized quinoxalines can be obtained with good to excellent yields by virtue of this method. The reaction features a broad substrate scope, the regulation of product distribution, scalable preparation and high atomic economy. The reaction mechanism was investigated in detail.

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来源期刊

Organic Chemistry Frontiers CHEMISTRY, ORGANIC-

CiteScore

7.90

自引率

11.10%

发文量

686

审稿时长

1 months

期刊介绍： Organic Chemistry Frontiers is an esteemed journal that publishes high-quality research across the field of organic chemistry. It places a significant emphasis on studies that contribute substantially to the field by introducing new or significantly improved protocols and methodologies. The journal covers a wide array of topics which include, but are not limited to, organic synthesis, the development of synthetic methodologies, catalysis, natural products, functional organic materials, supramolecular and macromolecular chemistry, as well as physical and computational organic chemistry.