Gene therapy for deafness: we can do more

IF 39.1 1区生物学 Q1 GENETICS & HEREDITY

Nature Reviews Genetics Pub Date : 2024-12-18 DOI:10.1038/s41576-024-00809-8

Yuxin Chen, Jiake Zhong, Yilai Shu

引用次数: 0

Abstract

Challenges in the development of treatments for hereditary hearing loss include the exploration of the underlying pathological mechanisms, the comprehensive evaluation of safety and efficacy of gene therapies in clinical trials, the optimization of surgical approaches for drug delivery, and effective collaboration between industry and academia. Gene therapy for congenital deafness has made a breakthrough in recent clinical trials. However, more work is needed to develop successful treatments for hereditary hearing loss, as the authors argue in this Comment.

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来源期刊

Nature Reviews Genetics 生物-遗传学

CiteScore

57.40

自引率

0.50%

发文量

113

审稿时长

6-12 weeks

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