Investigating the Association Between Hashimoto's Thyroiditis and Papillary Thyroid Cancer.

IF 2.3 3区 医学 Q1 OTORHINOLARYNGOLOGY
Adriana I Báez Berríos, Mathilda Monaghan, Margaret Brandwein-Weber, Maaike van Gerwen
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引用次数: 0

Abstract

Background: Hashimoto's thyroiditis' (HT) impact on the aggressive lymph node (ALN) status of papillary thyroid carcinoma (PTC) remains understudied.

Methods: Univariate and multivariate analyses assessed PTC aggressiveness markers, comparing PTC + HT to PTC alone from a single center retrospectively. ALN categorization included > 5 positive, ≥ 1 > 3 cm, and/or ≥ 4 with extranodal extension lymph nodes.

Results: Of 533 patients with PTC, 19.1% concurrently had HT. Compared to PTC alone, PTC + HT patients were predominantly female (p < 0.001), younger (p = 0.034), non-smokers (p = 0.035), and had more pN0 stage tumors (p < 0.001). PTC + HT was associated with lower odds of pN1 stage (ORadj, 0.50) and lymphatic invasion (ORadj, 0.53). No significant differences were observed in ALN status, pT stage, lymphatic and perineural invasion, gross ETE, margin, and focality.

Conclusion: ALN status does not differ between PTC with or without HT.

调查桥本氏甲状腺炎与甲状腺乳头状癌之间的关系
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来源期刊
CiteScore
7.00
自引率
6.90%
发文量
278
审稿时长
1.6 months
期刊介绍: Head & Neck is an international multidisciplinary publication of original contributions concerning the diagnosis and management of diseases of the head and neck. This area involves the overlapping interests and expertise of several surgical and medical specialties, including general surgery, neurosurgery, otolaryngology, plastic surgery, oral surgery, dermatology, ophthalmology, pathology, radiotherapy, medical oncology, and the corresponding basic sciences.
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