Palladium-Catalyzed Fluorinated Olefination of Aromatics

IF 4.9 1区 化学 Q1 CHEMISTRY, ORGANIC
Xin Liu, Yalong Li, Yilian Song, Jingyi Guo, Zechao Liu, Yingsheng Zhao
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引用次数: 0

Abstract

Palladium-mediated, ligand-promoted C–H fluorinated olefination of aromatic derivatives is reported employing 2-bromo-3,3,3-trifluoropropene (BTP) as the fluorinating reagent. Bioactive compounds, such as Isatin, exhibited excellent compatibility with this reaction, underscoring the significance of this methodology for the synthesis of important derivatives.

Abstract Image

报告采用 2-溴-3,3,3-三氟丙烯 (BTP) 作为氟化试剂,以钯为介导,配体促进芳香衍生物的 C-H 氟化烯化反应。生物活性化合物(如 Isatin)在这一反应中表现出极佳的兼容性,突出了这一方法在合成重要衍生物方面的重要性。
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来源期刊
Organic Letters
Organic Letters 化学-有机化学
CiteScore
9.30
自引率
11.50%
发文量
1607
审稿时长
1.5 months
期刊介绍: Organic Letters invites original reports of fundamental research in all branches of the theory and practice of organic, physical organic, organometallic,medicinal, and bioorganic chemistry. Organic Letters provides rapid disclosure of the key elements of significant studies that are of interest to a large portion of the organic community. In selecting manuscripts for publication, the Editors place emphasis on the originality, quality and wide interest of the work. Authors should provide enough background information to place the new disclosure in context and to justify the rapid publication format. Back-to-back Letters will be considered. Full details should be reserved for an Article, which should appear in due course.
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