The International Association for the Study of Lung Cancer Lung Cancer Staging Project: Application and Interpretation of the Residual Tumor (R) Classification for Lung Cancer. Results from an International Survey among Pathologists and Thoracic Surgeons.

IF 21 1区 医学 Q1 ONCOLOGY
Hans Hoffmann, Andrew G Nicholson, Frank C Detterbeck, Ming S Tsao, Marcin Ostrowski, Ramón Rami-Porta, Alain Borczuk, Mirella Marino, William D Travis, Paul E Van Schil, John Edwards
{"title":"The International Association for the Study of Lung Cancer Lung Cancer Staging Project: Application and Interpretation of the Residual Tumor (R) Classification for Lung Cancer. Results from an International Survey among Pathologists and Thoracic Surgeons.","authors":"Hans Hoffmann, Andrew G Nicholson, Frank C Detterbeck, Ming S Tsao, Marcin Ostrowski, Ramón Rami-Porta, Alain Borczuk, Mirella Marino, William D Travis, Paul E Van Schil, John Edwards","doi":"10.1016/j.jtho.2024.12.007","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>The study aimed to assess the opinion of pathologists and thoracic surgeons of the International Association for the Study of Lung Cancer (IASLC) regarding application and interpretation of the residual tumor (R) classification for lung cancer.</p><p><strong>Methods: </strong>Based on their membership-profile a total of n=623 pathologists and thoracic surgeons were identified and contacted by email with a cover letter and a link to an online survey. The questionnaire consisted of 12 questions about various aspects on application and interpretation of the R classification for lung cancer. The response rate (to at least one question) was 72% (144 pathologists and 303 surgeons).</p><p><strong>Results: </strong>Frequency of use of the R classification varies by geographic region. While R status is regularly reported in Europe and Asia, seventy percent of pathologists in the US or Canada never include R status on reports. Similar variation exists about who assigns the R category for the resection - in Europe and the UK it is mainly the pathologist, whilst in China/Japan and US it is the surgeon. There are some good agreements about margins examined and how to manage staple lines. The category \"uncertain resection\" R(un) has not been practically implemented in most of the world, except at some centers in Japan and the UK.</p><p><strong>Conclusion: </strong>This survey shows that surgical resection margins are part of routine reporting in most institutions, but assignment of an R category is not always part of the pathology report, with considerable variation between countries. Application of R(un) has not been taken up by most institutions, despite IASLC proposals, and further evidence is needed.</p>","PeriodicalId":17515,"journal":{"name":"Journal of Thoracic Oncology","volume":" ","pages":""},"PeriodicalIF":21.0000,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Thoracic Oncology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.jtho.2024.12.007","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Objective: The study aimed to assess the opinion of pathologists and thoracic surgeons of the International Association for the Study of Lung Cancer (IASLC) regarding application and interpretation of the residual tumor (R) classification for lung cancer.

Methods: Based on their membership-profile a total of n=623 pathologists and thoracic surgeons were identified and contacted by email with a cover letter and a link to an online survey. The questionnaire consisted of 12 questions about various aspects on application and interpretation of the R classification for lung cancer. The response rate (to at least one question) was 72% (144 pathologists and 303 surgeons).

Results: Frequency of use of the R classification varies by geographic region. While R status is regularly reported in Europe and Asia, seventy percent of pathologists in the US or Canada never include R status on reports. Similar variation exists about who assigns the R category for the resection - in Europe and the UK it is mainly the pathologist, whilst in China/Japan and US it is the surgeon. There are some good agreements about margins examined and how to manage staple lines. The category "uncertain resection" R(un) has not been practically implemented in most of the world, except at some centers in Japan and the UK.

Conclusion: This survey shows that surgical resection margins are part of routine reporting in most institutions, but assignment of an R category is not always part of the pathology report, with considerable variation between countries. Application of R(un) has not been taken up by most institutions, despite IASLC proposals, and further evidence is needed.

研究目的该研究旨在评估国际肺癌研究协会(IASLC)的病理学家和胸外科医生对肺癌残留肿瘤(R)分类的应用和解释的看法:根据他们的会员情况,共确定了 623 名病理学家和胸外科医生,并通过电子邮件与他们取得联系,同时附上一封求职信和一个在线调查的链接。调查问卷包括 12 个问题,涉及肺癌 R 分类的应用和解释的各个方面。回答率(至少回答一个问题)为 72%(144 名病理学家和 303 名外科医生):结果:R分类的使用频率因地理区域而异。欧洲和亚洲经常报告 R 状态,而美国或加拿大 70% 的病理学家从未在报告中列入 R 状态。在欧洲和英国,主要由病理学家指定切除术的 R 分类,而在中国/日本和美国,则由外科医生指定。在检查边缘和如何处理缝合线方面有一些很好的共识。除日本和英国的一些中心外,"不确定切除 "R(un)类别在世界大多数国家尚未实际实施:这项调查显示,手术切除边缘是大多数机构常规报告的一部分,但R类别的指定并不总是病理报告的一部分,各国之间存在很大差异。尽管国际癌症分类委员会(IASLC)提出了建议,但大多数机构并未采用R(un),因此还需要进一步的证据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Journal of Thoracic Oncology
Journal of Thoracic Oncology 医学-呼吸系统
CiteScore
36.00
自引率
3.90%
发文量
1406
审稿时长
13 days
期刊介绍: Journal of Thoracic Oncology (JTO), the official journal of the International Association for the Study of Lung Cancer,is the primary educational and informational publication for topics relevant to the prevention, detection, diagnosis, and treatment of all thoracic malignancies.The readship includes epidemiologists, medical oncologists, radiation oncologists, thoracic surgeons, pulmonologists, radiologists, pathologists, nuclear medicine physicians, and research scientists with a special interest in thoracic oncology.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信