Conditional and Unconditional Social Transfers, Early-Life Nutrition, and Child Growth

IF 24.7 1区 医学 Q1 PEDIATRICS
Jordyn T. Wallenborn, Souliviengkham Sonephet, Somphou Sayasone, Latsamy Siengsounthone, Sengchanh Kounnavong, Günther Fink
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引用次数: 0

Abstract

ImportanceRates of exclusive breastfeeding are declining despite the numerous benefits to mothers and their children.ObjectiveTo assess the effectiveness of conditional and unconditional social transfers on exclusive breastfeeding rates and child growth.Design, Setting, and ParticipantsThis is a prospective, parallel, 3-armed randomized clinical trial conducted between August 2022 and October 2023. The trial was conducted in 4 districts of Vientiane, Lao People’s Democratic Republic. Mothers identified from a large birth cohort were randomized into 2 intervention groups (conditional social transfer or unconditional social transfer) or a control group at a ratio of 1:1:1. Data analysis was conducted from December 2023 to January 2024.InterventionsTwo interventions were tested: (1) conditional social transfer, in which the mother received the social transfer only if still exclusively breastfeeding at 6 months, and (2) unconditional social transfer, in which the mother received the social transfer at 6 months regardless of breastfeeding status. Mothers in the control group received educational material only.Main Outcomes and MeasuresThe primary outcome was the proportion of women exclusively breastfeeding at 6 months post partum. Secondary outcomes included exclusive breastfeeding duration (in months) and child growth (height, weight, and head circumference).ResultsA total of 298 mothers (mean [SD] age, 27.2 [6.5] years) were identified from a large birth cohort and randomized into a conditional social transfer group (n = 100), an unconditional social transfer group (n = 97), or a control group (n = 101). The adjusted odds ratio of exclusive breastfeeding at 6 months post partum was 4.60 (95% CI, 2.10-10.07; P &amp;lt; .001) for the conditional social transfer group and 2.51 (95% CI, 1.11-5.66; P = .03) for the unconditional social transfer group compared with the control group. The risk of early exclusive breastfeeding cessation was lower for participants who received the unconditional social transfer (adjusted hazard ratio [aHR], 0.68; 95% CI, 0.49-0.92; P = .02) or conditional social transfer (aHR, 0.60; 95% CI, 0.44-0.83; P = .002) compared with participants in the control group. There were no significant differences between groups for child growth at 6 months post partum.Conclusions and RelevanceThe findings suggest that social transfers can substantially improve exclusive breastfeeding rates at 6 months post partum, with particularly large benefits for conditional transfers. Continued evaluation at 1, 2, and 3 years post partum will be conducted to assess the long-term outcomes of social transfers on complementary breastfeeding and child health and development over time.Trial RegistrationClinicalTrials.gov Identifier: NCT05665049
重要性尽管纯母乳喂养对母亲及其子女有诸多益处,但纯母乳喂养率却在下降。目标评估有条件和无条件社会转移对纯母乳喂养率和儿童生长的影响。设计、地点和参与者这是一项前瞻性、平行、三军随机临床试验,于 2022 年 8 月至 2023 年 10 月间进行。试验在老挝人民民主共和国万象市的 4 个区进行。从一个大型出生队列中确定的母亲按 1:1:1 的比例被随机分配到两个干预组(有条件社会转移或无条件社会转移)或对照组。干预措施测试了两种干预措施:(1) 有条件的社会转移支付,即母亲只有在 6 个月时仍然纯母乳喂养,才能获得社会转移支付;(2) 无条件的社会转移支付,即母亲无论母乳喂养状况如何,都能在 6 个月时获得社会转移支付。主要结果和测量指标主要结果是产后 6 个月时纯母乳喂养的妇女比例。结果 从一个大型出生队列中确定了 298 名母亲(平均 [SD] 年龄,27.2 [6.5] 岁),并将她们随机分为有条件社会转移支付组(n = 100)、无条件社会转移支付组(n = 97)或对照组(n = 101)。与对照组相比,有条件社会转移支付组产后 6 个月纯母乳喂养的调整赔率为 4.60 (95% CI, 2.10-10.07; P &amp;lt; .001),无条件社会转移支付组为 2.51 (95% CI, 1.11-5.66; P = .03)。与对照组相比,接受无条件社会转移支付(调整后危险比 [aHR],0.68;95% CI,0.49-0.92;P = .02)或有条件社会转移支付(aHR,0.60;95% CI,0.44-0.83;P = .002)的参与者过早停止纯母乳喂养的风险较低。结论和相关性研究结果表明,社会转移支付可以大幅提高产后 6 个月的纯母乳喂养率,有条件的社会转移支付尤其能带来巨大收益。将在产后 1 年、2 年和 3 年继续进行评估,以评估社会转移对补充性母乳喂养以及儿童健康和发育的长期影响:NCT05665049
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来源期刊
JAMA Pediatrics
JAMA Pediatrics PEDIATRICS-
CiteScore
31.60
自引率
1.90%
发文量
357
期刊介绍: JAMA Pediatrics, the oldest continuously published pediatric journal in the US since 1911, is an international peer-reviewed publication and a part of the JAMA Network. Published weekly online and in 12 issues annually, it garners over 8.4 million article views and downloads yearly. All research articles become freely accessible online after 12 months without any author fees, and through the WHO's HINARI program, the online version is accessible to institutions in developing countries. With a focus on advancing the health of infants, children, and adolescents, JAMA Pediatrics serves as a platform for discussing crucial issues and policies in child and adolescent health care. Leveraging the latest technology, it ensures timely access to information for its readers worldwide.
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