Nader Khani, Mojtaba Bonyadi, Roya Abedi Soleimani, Reza Hazrati Raziabad, Mehdi Ahmadi, Aziz Homayouni-Rad
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引用次数: 0
Abstract
Celiac disease (CD) can be considered an autoimmune problem, a disease caused by gluten sensitivity in the body. Gluten is found in foods such as barley, wheat, and rye. This ailment manifests in individuals with hereditary susceptibility and under the sway of environmental stimulants, counting, in addition to gluten and intestinal microbiota dysbiosis. Currently, the only recommended treatment for this condition is to follow a gluten-free diet for life. In this review, we scrutinized the studies of recent years that focused on the use of postbiotics in vitro and in vivo in CD. The investigation of postbiotics in CD could be intriguing to observe their diverse effects on several pathways. This study highlights the definitions, characteristics, and safety issues of postbiotics and their possible biological role in the prevention and treatment of CD, as well as their application in the food and drug industry.
乳糜泻（CD）可被视为一种自身免疫问题，是一种由体内麸质敏感引起的疾病。麸质存在于大麦、小麦和黑麦等食物中。除了麸质和肠道微生物菌群失调外，这种疾病还表现为遗传易感性和环境刺激物的影响。目前，唯一推荐的治疗方法是终身遵循无麸质饮食。在这篇综述中，我们仔细研究了近年来关于在 CD 体外和体内使用益生元的研究。对 CD 中益生元的研究可以观察到它们对多种途径的不同影响。本研究强调了益生菌后的定义、特点和安全性问题，以及它们在预防和治疗 CD 方面可能发挥的生物学作用，以及它们在食品和药品行业中的应用。
期刊介绍：
Probiotics and Antimicrobial Proteins publishes reviews, original articles, letters and short notes and technical/methodological communications aimed at advancing fundamental knowledge and exploration of the applications of probiotics, natural antimicrobial proteins and their derivatives in biomedical, agricultural, veterinary, food, and cosmetic products. The Journal welcomes fundamental research articles and reports on applications of these microorganisms and substances, and encourages structural studies and studies that correlate the structure and functional properties of antimicrobial proteins.
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