Prevalence and correlates of alexithymia in drug-resistant epilepsies.

IF 2.3 3区医学 Q2 BEHAVIORAL SCIENCES

Epilepsy & Behavior Pub Date : 2024-12-13 DOI:10.1016/j.yebeh.2024.110222

O Paradas, S Pradier, M Dessilas, A Viaud, L Chibani, M De-Montaudouin, A Gradel, V Michel, J Aupy

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引用次数: 0

Abstract

Introduction: Alexithymia, characterized by difficulty identifying and expressing emotions, is commonly observed in individuals with psychiatric and neurological disorders. However, its prevalence in patients with epilepsy (PWE), particularly in those with drug-resistant epilepsy (DRE), remains under-researched. This study investigates the prevalence of alexithymia in patients with DRE and explores its associated factors.

Methods: We conducted a retrospective observational study of 118 adult patients with focal DRE undergoing presurgical evaluation at Bordeaux University Hospital. Alexithymia was assessed using the Toronto Alexithymia Scale-20 (TAS-20), while psychiatric symptoms were evaluated with validated scales. Data on demographic characteristics, epilepsy duration, seizure frequency, antiepileptic drug use, and localization of the epileptogenic zone (EZ) were collected and analyzed using logistic regression models.

Results: Alexithymia was identified in 40.7 % of patients. Depression and anxiety were significantly associated with alexithymia (p < 0.01), whereas no correlation was observed between alexithymia and the localization or lateralization of the EZ.

Discussion: These findings suggest that alexithymia is prevalent among patients with DRE, with significant associations to depression and anxiety. The high prevalence of affective symptoms underscores the importance of early identification and intervention for alexithymia to improve outcomes in patients with DRE.

查看原文本刊更多论文

抗药性癫痫患者的亚历山大症发病率及相关因素。

前言情感缺失症（Alexithymia）以难以识别和表达情感为特征，常见于精神和神经疾病患者。然而，对其在癫痫患者（PWE），尤其是耐药性癫痫患者（DRE）中的发病率研究仍然不足。本研究调查了无情感障碍在抗药性癫痫患者中的患病率，并探讨了与之相关的因素：我们对波尔多大学医院接受手术前评估的 118 名局灶性 DRE 成年患者进行了回顾性观察研究。亚历渴症采用多伦多亚历渴症量表-20（TAS-20）进行评估，精神症状则采用有效量表进行评估。研究人员收集了人口统计学特征、癫痫持续时间、癫痫发作频率、抗癫痫药物使用情况以及致痫区（EZ）定位等数据，并使用逻辑回归模型进行了分析：结果发现，40.7%的患者患有亚历山大症。抑郁和焦虑与亚历山大症明显相关（P 讨论）：这些研究结果表明，失认症在 DRE 患者中很普遍，与抑郁和焦虑密切相关。情感症状的高流行率强调了早期识别和干预情感障碍以改善眩晕症患者预后的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Epilepsy & Behavior 医学-行为科学

CiteScore

5.40

自引率

15.40%

发文量

385

审稿时长

43 days

期刊介绍： Epilepsy & Behavior is the fastest-growing international journal uniquely devoted to the rapid dissemination of the most current information available on the behavioral aspects of seizures and epilepsy. Epilepsy & Behavior presents original peer-reviewed articles based on laboratory and clinical research. Topics are drawn from a variety of fields, including clinical neurology, neurosurgery, neuropsychiatry, neuropsychology, neurophysiology, neuropharmacology, and neuroimaging. From September 2012 Epilepsy & Behavior stopped accepting Case Reports for publication in the journal. From this date authors who submit to Epilepsy & Behavior will be offered a transfer or asked to resubmit their Case Reports to its new sister journal, Epilepsy & Behavior Case Reports.