Jianyu Dong, Shaofeng Wu, Long Liu, Dan Zhou, Min Mo, Ya-Dong Gao, Lebin Su, Shuang-Feng Yin, Yongbo Zhou
{"title":"Iminonaphthofuranone synthesis via multiple-component cyclization of 2-naphthols using only molecular oxygen","authors":"Jianyu Dong, Shaofeng Wu, Long Liu, Dan Zhou, Min Mo, Ya-Dong Gao, Lebin Su, Shuang-Feng Yin, Yongbo Zhou","doi":"10.1039/d4qo01939c","DOIUrl":null,"url":null,"abstract":"A multiple-component oxidative cyclization of easily available 2-naphthols, anilines, and ethyl glyoxylate is successfully achieved using only molecular oxygen. The reaction enables green, efficient and highly selective synthesis of iminonaphthofuranones, a category of disperse dyes that are previously inaccessible. The products exhibit a wide spectrum of colors, adjustable from pale orange to dark purple. They are also readily transformed into naphthofuranones and highly functionalized naphthols.","PeriodicalId":97,"journal":{"name":"Organic Chemistry Frontiers","volume":"42 1","pages":""},"PeriodicalIF":4.6000,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Organic Chemistry Frontiers","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1039/d4qo01939c","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 0
Abstract
A multiple-component oxidative cyclization of easily available 2-naphthols, anilines, and ethyl glyoxylate is successfully achieved using only molecular oxygen. The reaction enables green, efficient and highly selective synthesis of iminonaphthofuranones, a category of disperse dyes that are previously inaccessible. The products exhibit a wide spectrum of colors, adjustable from pale orange to dark purple. They are also readily transformed into naphthofuranones and highly functionalized naphthols.
期刊介绍:
Organic Chemistry Frontiers is an esteemed journal that publishes high-quality research across the field of organic chemistry. It places a significant emphasis on studies that contribute substantially to the field by introducing new or significantly improved protocols and methodologies. The journal covers a wide array of topics which include, but are not limited to, organic synthesis, the development of synthetic methodologies, catalysis, natural products, functional organic materials, supramolecular and macromolecular chemistry, as well as physical and computational organic chemistry.