Jonathan Mitton, Muhammad E Khan, Daniel Combs, Sairam Parthasarathy, Saif Mashaqi
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引用次数: 0
Abstract
Obstructive sleep apnea is one of the most common sleep disorders. Positive airway pressure therapy is considered the gold standard for treating obstructive sleep apnea. Yet, optimal therapy might not be achieved in some cases of severe obstructive sleep apnea, despite using maximum settings. In this case report, we describe the successful combination of positive airway pressure therapy and atomoxetine-oxybutynin in reducing the apnea-hypopnea index from the severe range to the mild to moderate range. This was also associated with significant improvement in several symptoms including excessive daytime sleepiness and drowsiness while driving.
Citation: Mitton J, Khan ME, Combs D, Parthasarathy S, Mashaqi S. Images: combined positive air way pressure and atomoxetine-oxybutynin for the treatment of severe obstructive sleep apnea. J Clin Sleep Med. 2025;21(4):743-746.
阻塞性睡眠呼吸暂停（OSA）是最常见的睡眠障碍之一。气道正压疗法（PAP）被认为是治疗 OSA 的黄金标准。然而，在一些严重的 OSA 病例中，尽管使用了最大设置，也可能无法达到最佳治疗效果。在本病例报告中，我们描述了正压气道疗法与阿托西汀-奥布宁的成功结合，将呼吸暂停-低通气指数从重度范围降至轻度至中度范围。同时，包括白天过度嗜睡和开车时嗜睡在内的一些症状也得到了明显改善。
期刊介绍：
Journal of Clinical Sleep Medicine focuses on clinical sleep medicine. Its emphasis is publication of papers with direct applicability and/or relevance to the clinical practice of sleep medicine. This includes clinical trials, clinical reviews, clinical commentary and debate, medical economic/practice perspectives, case series and novel/interesting case reports. In addition, the journal will publish proceedings from conferences, workshops and symposia sponsored by the American Academy of Sleep Medicine or other organizations related to improving the practice of sleep medicine.
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