Anterior circulation stroke mechanical thrombectomy with transradial balloon guide catheter: Single-center pilot study

IF 1.8 4区 医学 Q3 CLINICAL NEUROLOGY
Mpuekela Tshibangu, Peter Theiss, Tatiana Abou-Mrad, Laura Stone McGuire, Adrusht Madapoosi, Ali Alaraj
{"title":"Anterior circulation stroke mechanical thrombectomy with transradial balloon guide catheter: Single-center pilot study","authors":"Mpuekela Tshibangu,&nbsp;Peter Theiss,&nbsp;Tatiana Abou-Mrad,&nbsp;Laura Stone McGuire,&nbsp;Adrusht Madapoosi,&nbsp;Ali Alaraj","doi":"10.1016/j.clineuro.2024.108670","DOIUrl":null,"url":null,"abstract":"<div><h3>Objectives</h3><div>This study evaluates the feasibility, safety, and efficiency of using a balloon guide catheter (BGC) through transradial access (TRA) for mechanical thrombectomy (MT) in patients with anterior circulation strokes.</div></div><div><h3>Methods</h3><div>A retrospective case series of patients who underwent MT using BGC through TRA for acute ischemic stroke in the anterior circulation was conducted. Data collected included procedural times (from puncture to revascularization), technical success, complication rates, and clinical outcomes. Patients’ baseline characteristics, stroke severity, and post-procedural outcomes were also analyzed.</div></div><div><h3>Results</h3><div>Thirty patients were included, with a mean age of 64.4 ± 13.6 years. The median admission NIHSS score was 13, and 17 % received intravenous thrombolysis before thrombectomy. Right-sided occlusions were more frequent (57 %). TRA was successful in 27 patients (90 %), with 3 (10 %) requiring conversion to femoral access. The median puncture-to-revascularization time was 32 minutes, and first-pass revascularization was achieved in 40 % of cases. A favorable TICI 2b or higher was accomplished in 97 %, with no access site complications. Hemorrhagic conversion occurred in 20 %, including one symptomatic intracerebral hemorrhage (3 %). At discharge, 57 % of patients had favorable outcomes (mRS 0–2), and by 90 days, 54 % achieved functional independence, with a mortality rate of 3 %.</div></div><div><h3>Conclusion</h3><div>This case series highlights the feasibility of using BGC through TRA in MT for anterior circulation strokes, demonstrating promising safety and efficiency. Future multicenter studies with larger cohorts are necessary to compare clinical outcomes of TRA versus transfemoral access and guide standardized protocols for stroke interventions.</div></div>","PeriodicalId":10385,"journal":{"name":"Clinical Neurology and Neurosurgery","volume":"249 ","pages":"Article 108670"},"PeriodicalIF":1.8000,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Neurology and Neurosurgery","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0303846724005572","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Objectives

This study evaluates the feasibility, safety, and efficiency of using a balloon guide catheter (BGC) through transradial access (TRA) for mechanical thrombectomy (MT) in patients with anterior circulation strokes.

Methods

A retrospective case series of patients who underwent MT using BGC through TRA for acute ischemic stroke in the anterior circulation was conducted. Data collected included procedural times (from puncture to revascularization), technical success, complication rates, and clinical outcomes. Patients’ baseline characteristics, stroke severity, and post-procedural outcomes were also analyzed.

Results

Thirty patients were included, with a mean age of 64.4 ± 13.6 years. The median admission NIHSS score was 13, and 17 % received intravenous thrombolysis before thrombectomy. Right-sided occlusions were more frequent (57 %). TRA was successful in 27 patients (90 %), with 3 (10 %) requiring conversion to femoral access. The median puncture-to-revascularization time was 32 minutes, and first-pass revascularization was achieved in 40 % of cases. A favorable TICI 2b or higher was accomplished in 97 %, with no access site complications. Hemorrhagic conversion occurred in 20 %, including one symptomatic intracerebral hemorrhage (3 %). At discharge, 57 % of patients had favorable outcomes (mRS 0–2), and by 90 days, 54 % achieved functional independence, with a mortality rate of 3 %.

Conclusion

This case series highlights the feasibility of using BGC through TRA in MT for anterior circulation strokes, demonstrating promising safety and efficiency. Future multicenter studies with larger cohorts are necessary to compare clinical outcomes of TRA versus transfemoral access and guide standardized protocols for stroke interventions.
前循环卒中机械取栓经桡动脉球囊导尿管:单中心先导研究。
目的:本研究评估球囊导尿管(BGC)经桡动脉通路(TRA)用于前循环卒中患者机械取栓(MT)的可行性、安全性和有效性。方法:回顾性分析经TRA行BGC治疗急性缺血性脑卒中患者的病例系列。收集的数据包括手术时间(从穿刺到血运重建术)、技术成功率、并发症发生率和临床结果。还分析了患者的基线特征、卒中严重程度和术后结果。结果:纳入患者30例,平均年龄64.4 ± 13.6岁。入院NIHSS评分中位数为13分,17% %患者在取栓前接受静脉溶栓。右侧闭塞更常见(57 %)。27例(90 %)患者TRA成功,3例(10 %)需要转股通路。穿刺至血运重建的中位时间为32 分钟,40%的病例实现了第一次血运重建。97% %的患者达到良好的TICI 2b或更高,无通路并发症。20 %发生出血转化,包括1例症状性脑出血(3 %)。出院时,57 %的患者预后良好(mRS 0-2),到90天,54 %的患者实现了功能独立,死亡率为3 %。结论:本病例系列强调了通过TRA在MT治疗前循环卒中中应用BGC的可行性,显示出良好的安全性和有效性。未来需要更大队列的多中心研究来比较TRA与经股动脉通路的临床结果,并指导卒中干预的标准化方案。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Clinical Neurology and Neurosurgery
Clinical Neurology and Neurosurgery 医学-临床神经学
CiteScore
3.70
自引率
5.30%
发文量
358
审稿时长
46 days
期刊介绍: Clinical Neurology and Neurosurgery is devoted to publishing papers and reports on the clinical aspects of neurology and neurosurgery. It is an international forum for papers of high scientific standard that are of interest to Neurologists and Neurosurgeons world-wide.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信