The first case of Aspergillus fumigatus with high-level resistance to voriconazole due to the TR46/Y121F/T289A mutation in the Russian Federation

IF 2.1 4区医学 Q3 INFECTIOUS DISEASES

Diagnostic microbiology and infectious disease Pub Date : 2024-11-22 DOI:10.1016/j.diagmicrobio.2024.116624

Galina Klyasova, Anna Malchikova, Svetlana Khrulnova

引用次数: 0

Abstract

We report the first case of voriconazole-resistant A. fumigatus with the TR₄₆/Y121F/T289A mutation in the Russian Federation, identified in a 43-year-old woman with acute lymphoblastic leukemia after allogeneic hematopoietic stem cell transplantation.

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俄罗斯联邦第一例因TR46/Y121F/T289A突变而对伏立康唑产生高水平耐药性的烟曲霉病例。

我们报告了俄罗斯联邦首例携带TR46/Y121F/T289A突变的伏立康唑耐药烟曲霉，该病例发现于一名43岁的女性，她在接受同种异体造血干细胞移植后患有急性淋巴细胞白血病。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Diagnostic microbiology and infectious disease 医学-传染病学

CiteScore

5.30

自引率

3.40%

发文量

149

审稿时长

56 days

期刊介绍： Diagnostic Microbiology and Infectious Disease keeps you informed of the latest developments in clinical microbiology and the diagnosis and treatment of infectious diseases. Packed with rigorously peer-reviewed articles and studies in bacteriology, immunology, immunoserology, infectious diseases, mycology, parasitology, and virology, the journal examines new procedures, unusual cases, controversial issues, and important new literature. Diagnostic Microbiology and Infectious Disease distinguished independent editorial board, consisting of experts from many medical specialties, ensures you extensive and authoritative coverage.