A case of anaplastic oligodendroglioma in a rabbit (Oryctolagus cuniculus).

IF 1.1 4区 农林科学 Q3 VETERINARY SCIENCES
Journal of Veterinary Medical Science Pub Date : 2025-01-10 Epub Date: 2024-12-03 DOI:10.1292/jvms.24-0438
Hisaki Tokuno, Miyuu Tanaka, Takeshi Izawa, Hiroshi Sasai, Mitsuru Kuwamura
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引用次数: 0

Abstract

A 6-year-old male rabbit (Oryctolagus cuniculus) showed loss of appetite, right side rotating and the left side circling. The symptoms did not improve, and the rabbit died on the 2nd day after presentation. Histological evaluation of the brain revealed a non-demarcated high cellularity area of neoplastic cells in the midbrain. In the lesion, neoplastic proliferation of large pleomorphic cells with irregular nuclei and medium amount of cytoplasm with prominent atypia was observed. Most of the neoplastic cells were immunohistochemically positive for both Olig2 and vimentin, and filamentous structure was seen in the cytoplasm. To our knowledge, this is the first report of anaplastic oligodendroglioma in a pet rabbit.

兔间变性少突胶质细胞瘤1例。
6岁雄性兔(Oryctolagus cuniculus)表现为食欲不振,右侧旋转,左侧旋转。症状无改善,出现后第2天死亡。脑组织的组织学检查显示在中脑有一个未划分的高细胞区肿瘤细胞。病灶内可见核不规则的大多形性细胞增生,胞质中量,异型性明显。多数肿瘤细胞Olig2和vimentin免疫组化均阳性,胞质呈丝状结构。据我们所知,这是第一次报道在宠物兔子身上发生间变性少突胶质细胞瘤。
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来源期刊
Journal of Veterinary Medical Science
Journal of Veterinary Medical Science 农林科学-兽医学
CiteScore
2.30
自引率
8.30%
发文量
230
审稿时长
9-18 weeks
期刊介绍: JVMS is a peer-reviewed journal and publishes a variety of papers on veterinary science from basic research to applied science and clinical research. JVMS is published monthly and consists of twelve issues per year. Papers are from the areas of anatomy, physiology, pharmacology, toxicology, pathology, immunology, microbiology, virology, parasitology, internal medicine, surgery, clinical pathology, theriogenology, avian disease, public health, ethology, and laboratory animal science. Although JVMS has played a role in publishing the scientific achievements of Japanese researchers and clinicians for many years, it now also accepts papers submitted from all over the world.
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