{"title":"A case of anaplastic oligodendroglioma in a rabbit (Oryctolagus cuniculus).","authors":"Hisaki Tokuno, Miyuu Tanaka, Takeshi Izawa, Hiroshi Sasai, Mitsuru Kuwamura","doi":"10.1292/jvms.24-0438","DOIUrl":null,"url":null,"abstract":"<p><p>A 6-year-old male rabbit (Oryctolagus cuniculus) showed loss of appetite, right side rotating and the left side circling. The symptoms did not improve, and the rabbit died on the 2nd day after presentation. Histological evaluation of the brain revealed a non-demarcated high cellularity area of neoplastic cells in the midbrain. In the lesion, neoplastic proliferation of large pleomorphic cells with irregular nuclei and medium amount of cytoplasm with prominent atypia was observed. Most of the neoplastic cells were immunohistochemically positive for both Olig2 and vimentin, and filamentous structure was seen in the cytoplasm. To our knowledge, this is the first report of anaplastic oligodendroglioma in a pet rabbit.</p>","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":""},"PeriodicalIF":1.1000,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Veterinary Medical Science","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1292/jvms.24-0438","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
A 6-year-old male rabbit (Oryctolagus cuniculus) showed loss of appetite, right side rotating and the left side circling. The symptoms did not improve, and the rabbit died on the 2nd day after presentation. Histological evaluation of the brain revealed a non-demarcated high cellularity area of neoplastic cells in the midbrain. In the lesion, neoplastic proliferation of large pleomorphic cells with irregular nuclei and medium amount of cytoplasm with prominent atypia was observed. Most of the neoplastic cells were immunohistochemically positive for both Olig2 and vimentin, and filamentous structure was seen in the cytoplasm. To our knowledge, this is the first report of anaplastic oligodendroglioma in a pet rabbit.
期刊介绍:
JVMS is a peer-reviewed journal and publishes a variety of papers on veterinary science from basic research to applied science and clinical research. JVMS is published monthly and consists of twelve issues per year. Papers are from the areas of anatomy, physiology, pharmacology, toxicology, pathology, immunology, microbiology, virology, parasitology, internal medicine, surgery, clinical pathology, theriogenology, avian disease, public health, ethology, and laboratory animal science. Although JVMS has played a role in publishing the scientific achievements of Japanese researchers and clinicians for many years, it now also accepts papers submitted from all over the world.