{"title":"PRDX6 as an additional piece in the puzzle of selenoprotein synthesis","authors":"Maria Schwarz, Anna Patricia Kipp","doi":"10.1016/j.molcel.2024.11.010","DOIUrl":null,"url":null,"abstract":"In this issue of <em>Molecular Cell</em>, Ito et al.<span><span><sup>1</sup></span></span> and Chen et al.<span><span><sup>2</sup></span></span> identify peroxiredoxin 6 (PRDX6) as member of the selenoprotein (re)synthesis machinery, thereby linking PRDX6 to ferroptosis susceptibility of cancer cells.","PeriodicalId":18950,"journal":{"name":"Molecular Cell","volume":"262 1","pages":""},"PeriodicalIF":14.5000,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Molecular Cell","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1016/j.molcel.2024.11.010","RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
In this issue of Molecular Cell, Ito et al.1 and Chen et al.2 identify peroxiredoxin 6 (PRDX6) as member of the selenoprotein (re)synthesis machinery, thereby linking PRDX6 to ferroptosis susceptibility of cancer cells.
期刊介绍:
Molecular Cell is a companion to Cell, the leading journal of biology and the highest-impact journal in the world. Launched in December 1997 and published monthly. Molecular Cell is dedicated to publishing cutting-edge research in molecular biology, focusing on fundamental cellular processes. The journal encompasses a wide range of topics, including DNA replication, recombination, and repair; Chromatin biology and genome organization; Transcription; RNA processing and decay; Non-coding RNA function; Translation; Protein folding, modification, and quality control; Signal transduction pathways; Cell cycle and checkpoints; Cell death; Autophagy; Metabolism.