An assessment of the prevalence of Aflatoxin M1 level in milk and milk powder based on high performance liquid chromatography and dietary risk assessment.

Q1 Environmental Science
Toxicology Reports Pub Date : 2024-11-09 eCollection Date: 2024-12-01 DOI:10.1016/j.toxrep.2024.101787
Yaser Almasoud, Manar Alwelaie, Zeyad Aldosari, Sarah Alotaibi, Abdullah Alsayari, Ghada Alzyadi, Mohammed Almutairi, Sulaiman Alajel, Abdullah Al Tamim, Hibah Alharbi
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引用次数: 0

Abstract

Milk is susceptible to Aflatoxin M1 (AFM1) contamination, mainly through consumption of contaminated animal's feed. The natural occurrence of aflatoxin M1 (AFB1) has been surveyed in samples of milk and milk powder. Samples collected from different regions of Saudi Arabia during the period from 2013 to 2021 were subjected to high-performance liquid chromatography analysis, and (AFB1) was quantified with detection limits of 0.5 µg/kg. The Saudi Food and Drug Authority has taken strong actions to limit AFM1 contamination, increase aflatoxin control, and modify the regulations. A study analyzed 363 randomly collected milk samples (168 milk, 195 milk powder) from Saudi Arabia using LC-MS/MS. Out of the 363 samples, 20 were positive for AFM1, with 343 were within the limits. One out of the 168 milk samples and 19 out of the 195 milk powder samples exceeded the limits, with seven originating from Saudi Arabia. The highest AFM1 concentration (3.97 µg/kg) was found in the Saudi samples. Saudi Arabia's mycotoxin regulations significantly reduced AFM1 contamination in milk, which is not considered a serious health hazard.

基于高效液相色谱法和膳食风险评估的牛奶和奶粉中黄曲霉毒素M1水平的流行程度评估。
牛奶易受黄曲霉毒素M1 (AFM1)污染,主要是通过食用受污染的动物饲料。对牛奶和奶粉样品中黄曲霉毒素M1 (AFB1)的自然发生情况进行了调查。2013 - 2021年采集于沙特阿拉伯不同地区的样品进行高效液相色谱分析,(AFB1)定量,检出限为0.5 µg/kg。沙特食品和药物管理局已采取强有力的行动限制AFM1污染,加强黄曲霉毒素控制,并修改法规。本研究采用LC-MS/MS对随机采集的363份来自沙特阿拉伯的牛奶样品(168份牛奶,195份奶粉)进行了分析。在363份样本中,20份AFM1阳性,343份在限度内。168份牛奶样本中有1份超标,195份奶粉样本中有19份超标,其中7份来自沙特阿拉伯。沙特样品中AFM1浓度最高(3.97 µg/kg)。沙特阿拉伯的霉菌毒素法规大大减少了牛奶中的AFM1污染,这并不被认为是严重的健康危害。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Toxicology Reports
Toxicology Reports Environmental Science-Health, Toxicology and Mutagenesis
CiteScore
7.60
自引率
0.00%
发文量
228
审稿时长
11 weeks
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