Effect of traditional Chinese medicine on cardiovascular death and all-cause death among patients with heart failure and/or atrial fibrillation.

IF 3.2 3区医学 Q1 MEDICINE, GENERAL & INTERNAL

Internal and Emergency Medicine Pub Date : 2024-12-04 DOI:10.1007/s11739-024-03821-2

Wei-Syun Hu, Cheng-Li Lin

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引用次数: 0

Abstract

We tried to define the association of adverse cardiovascular (CV) events, such as CV death and all-cause death among patients with heart failure (HF) and/or atrial fibrillation (AF) receiving traditional Chinese medicine (TCM) or not. We used data from the Taiwan National Health Insurance Research Database in a retrospective cohort study using propensity scoring (PS) matching. We matched 54,859 and 18,307 patients each to the treatment vs. non-treatment group and found a significantly decreased risk of adverse CV events after PS score matching, suggesting that TCM reduces the risk of these adverse outcomes. Compared to HF patients without AF in non-TCM user, HF patients without AF in TCM user and HF patients with AF in TCM user had decreased risk of CV death by 0.50 times (95% CI 0.49, 0.52) and 0.84 times (95% CI 0.49,0.52), respectively. HF patients without AF in TCM user and HF patients with AF in TCM user had decreased risk of all-cause death relative to HF patients without AF in non-TCM user by 0.53 times (95% CI 0.52, 0.54) and 0.74 times (95% CI 0.72,0.76), respectively. The results said that there is significant reduction of decrease in risk of CV death and all death among the patients receiving TCM, especially those without AF.

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中药对心力衰竭和/或房颤患者心血管死亡和全因死亡的影响

我们试图确定不良心血管事件（CV）的相关性，如心血管死亡和全因死亡在心力衰竭（HF）和/或房颤（AF）患者中是否接受中药（TCM）。本研究采用倾向评分法（PS）进行回顾性队列研究。我们将54,859例和18,307例患者分别与治疗组和非治疗组进行了匹配，发现PS评分匹配后不良CV事件的风险显著降低，这表明中医药降低了这些不良结局的风险。与非中药服用者无房颤的HF患者相比，中药服用者无房颤的HF患者和中药服用者合并房颤的HF患者的CV死亡风险分别降低了0.50倍（95% CI 0.49,0.52）和0.84倍（95% CI 0.49,0.52）。与非中药服用者无房颤的HF患者相比，中药服用者无房颤的HF患者和中药服用者合并房颤的HF患者全因死亡风险分别降低0.53倍（95% CI 0.52, 0.54）和0.74倍（95% CI 0.72,0.76）。结果表明，在接受中医治疗的患者中，尤其是没有房颤的患者，心血管死亡和所有死亡的风险都有显著降低。

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来源期刊

Internal and Emergency Medicine 医学-医学：内科

CiteScore

7.20

自引率

4.30%

发文量

258

审稿时长

6-12 weeks

期刊介绍： Internal and Emergency Medicine (IEM) is an independent, international, English-language, peer-reviewed journal designed for internists and emergency physicians. IEM publishes a variety of manuscript types including Original investigations, Review articles, Letters to the Editor, Editorials and Commentaries. Occasionally IEM accepts unsolicited Reviews, Commentaries or Editorials. The journal is divided into three sections, i.e., Internal Medicine, Emergency Medicine and Clinical Evidence and Health Technology Assessment, with three separate editorial boards. In the Internal Medicine section, invited Case records and Physical examinations, devoted to underlining the role of a clinical approach in selected clinical cases, are also published. The Emergency Medicine section will include a Morbidity and Mortality Report and an Airway Forum concerning the management of difficult airway problems. As far as Critical Care is becoming an integral part of Emergency Medicine, a new sub-section will report the literature that concerns the interface not only for the care of the critical patient in the Emergency Department, but also in the Intensive Care Unit. Finally, in the Clinical Evidence and Health Technology Assessment section brief discussions of topics of evidence-based medicine (Cochrane’s corner) and Research updates are published. IEM encourages letters of rebuttal and criticism of published articles. Topics of interest include all subjects that relate to the science and practice of Internal and Emergency Medicine.