Facile Ru-catalysed synthesis of quinazolin-4(3H)-ones by tandem cyclization of 2-nitrobenzonitrile and alcohol derivatives under air.

IF 2.9 3区化学 Q1 CHEMISTRY, ORGANIC

Organic & Biomolecular Chemistry Pub Date : 2024-12-03 DOI:10.1039/d4ob01786b

Ban Van Phuc, Tien Dat Nguyen, Nguyen T Minh Tuan, Phuong Anh Dao, Phan T Thao Vy, Hien Nguyen, Ngoc Tuan Nguyen, Quoc Anh Ngo, Tran Quang Hung, Tuan Thanh Dang

引用次数: 0

Abstract

We have developed an efficient approach for the first Ru-catalysed synthesis of 2-arylquinazolin-4(3H)-ones from 2-nitrobenzonitriles and alcohols. This method features a broad substrate scope, high yields, and functional group tolerance and does not require any oxidant or reductant, allowing for simple, practical and sustainable synthesis.

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来源期刊

Organic & Biomolecular Chemistry 化学-有机化学

CiteScore

5.50

自引率

9.40%

发文量

1056

审稿时长

1.3 months

期刊介绍： Organic & Biomolecular Chemistry is an international journal using integrated research in chemistry-organic chemistry. Founded in 2003 by the Royal Society of Chemistry, the journal is published in Semimonthly issues and has been indexed by SCIE, a leading international database. The journal focuses on the key research and cutting-edge progress in the field of chemistry-organic chemistry, publishes and reports the research results in this field in a timely manner, and is committed to becoming a window and platform for rapid academic exchanges among peers in this field. The journal's impact factor in 2023 is 2.9, and its CiteScore is 5.5.