Precision Oncology: 2024 in Review

IF 29.7 1区医学 Q1 ONCOLOGY

Cancer discovery Pub Date : 2024-12-02 DOI:10.1158/2159-8290.cd-24-1476

Matteo Repetto, Nicole Fernandez, Alexander Drilon, Debyani Chakravarty

引用次数: 0

Abstract

Summary: This article discusses the specific advances made in precision oncology in 2024. We comment on the evolving nature of predictive molecular events used to select patients who will most benefit clinically from treatment. We also discuss advances in the development of strategic treatment regimens for combination therapies, rational drug design of small-molecule inhibitors, and structurally informed drug repurposing.

查看原文本刊更多论文

精密肿瘤学：2024年回顾

摘要：本文讨论了2024年精准肿瘤学的具体进展。我们评论了用于选择将从治疗中获益最多的临床患者的预测性分子事件的演变性质。我们还讨论了联合治疗的策略治疗方案的发展进展，小分子抑制剂的合理药物设计，以及结构上知情的药物再利用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Cancer discovery ONCOLOGY-

CiteScore

22.90

自引率

1.40%

发文量

838

审稿时长

6-12 weeks

期刊介绍： Cancer Discovery publishes high-impact, peer-reviewed articles detailing significant advances in both research and clinical trials. Serving as a premier cancer information resource, the journal also features Review Articles, Perspectives, Commentaries, News stories, and Research Watch summaries to keep readers abreast of the latest findings in the field. Covering a wide range of topics, from laboratory research to clinical trials and epidemiologic studies, Cancer Discovery spans the entire spectrum of cancer research and medicine.