Mixed Large Cell Neuroendocrine Carcinoma and Endometrioid Adenocarcinoma: A Rare Case Report with Review of Literature.

IF 1.2 Q3 OBSTETRICS & GYNECOLOGY
Journal of Mid-life Health Pub Date : 2024-07-01 Epub Date: 2024-10-17 DOI:10.4103/jmh.jmh_211_23
Vinay N Gowda, Meenakshi Rao, Shashank Shekhar, Parmod Kumar
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引用次数: 0

Abstract

We report the case of a 60-year-old female who presented with postmenopausal bleeding after she underwent investigations followed by a total abdominal hysterectomy with bilateral salpingo-oophorectomy and pelvic lymphadenectomy. A diagnosis of low-grade endometrioid adenocarcinoma admixed with large cell neuroendocrine carcinoma (NEC) was made based on the histomorphology and immunohistochemical profile. NEC of the endometrium is a rare and highly aggressive neoplasm requiring a multidisciplinary approach for its treatment. As treatment strategies are changing over time, preoperating imaging evaluation and histopathological examination with molecular characterization whenever possible are essential to follow, to offer the appropriate information to surgeons and/or oncologists for optimal management in these patients.

混合大细胞神经内分泌癌和子宫内膜样腺癌一例罕见报告并文献复习。
我们报告的情况下,60岁的女性谁提出绝经后出血,她接受调查后,全腹子宫切除术,双侧输卵管卵巢切除术和盆腔淋巴结切除术。根据组织形态学和免疫组织化学特征,诊断为低级别子宫内膜样腺癌合并大细胞神经内分泌癌(NEC)。子宫内膜NEC是一种罕见且高度侵袭性的肿瘤,需要多学科的治疗方法。随着治疗策略的不断变化,术前影像学评估和组织病理学检查与分子表征是必要的,尽可能遵循,为外科医生和/或肿瘤学家提供适当的信息,以优化这些患者的管理。
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来源期刊
Journal of Mid-life Health
Journal of Mid-life Health Social Sciences-Health (social science)
CiteScore
1.70
自引率
9.10%
发文量
39
审稿时长
43 weeks
期刊介绍: Journal of mid-life health is the official journal of the Indian Menopause society published Quarterly in January, April, July and October. It is peer reviewed, scientific journal of mid-life health and its problems. It includes all aspects of mid-life health, preventive as well as curative. The journal publishes on subjects such as gynecology, neurology, geriatrics, psychiatry, endocrinology, urology, andrology, psychology, healthy ageing, cardiovascular health, bone health, quality of life etc. as relevant of men and women in their midlife. The Journal provides a visible platform to the researchers as well as clinicians to publish their experiences in this area thereby helping in the promotion of mid-life health leading to healthy ageing, growing need due to increasing life expectancy. The Editorial team has maintained high standards and published original research papers, case reports and review articles from the best of the best contributors both national & international, consistently so that now, it has become a great tool in the hands of menopause practitioners.
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