Metformin and monkeys: what can we learn about delaying aging?

IF 5.9 3区农林科学 Q1 VETERINARY SCIENCES

Lab Animal Pub Date : 2024-11-28 DOI:10.1038/s41684-024-01492-2

José Pedro Castro

引用次数: 0

Abstract

A new study reveals that metformin, a widely prescribed diabetes medication, can significantly improve health parameters in aged male cynomolgus monkeys — possibly by slowing the aging process. The findings represent an important step toward understanding how pharmaceutical interventions might, in the future, extend the healthspan and delay age-related diseases in humans.

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二甲双胍和猴子：我们能从延缓衰老中学到什么？

一项新的研究表明，二甲双胍，一种广泛使用的糖尿病药物，可以显著改善老年雄性食蟹猴的健康参数——可能是通过减缓衰老过程。这些发现代表了理解药物干预在未来如何延长人类健康寿命和延缓与年龄有关的疾病的重要一步。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Lab Animal 农林科学-兽医学

CiteScore

0.60

自引率

2.90%

发文量

181

审稿时长

>36 weeks

期刊介绍： LabAnimal is a Nature Research journal dedicated to in vivo science and technology that improves our basic understanding and use of model organisms of human health and disease. In addition to basic research, methods and technologies, LabAnimal also covers important news, business and regulatory matters that impact the development and application of model organisms for preclinical research. LabAnimal's focus is on innovative in vivo methods, research and technology covering a wide range of model organisms. Our broad scope ensures that the work we publish reaches the widest possible audience. LabAnimal provides a rigorous and fair peer review of manuscripts, high standards for copyediting and production, and efficient publication.