Current landscape and future perspectives in the pathogenesis and treatment of Pyoderma gangrenosum.

Abstract

Pyoderma gangrenosum is a rare, ulcerative neutrophilic dermatosis of yet unknown origin. While advances have been made into the mechanisms underlying PG, our understanding is limited by a paucity of research and funding into this condition. This review highlights the current landscape of PG pathogenesis, diagnosis, and treatment in the hopes of encouraging additional scientific inquiry into this rare, severe condition.