High-throughput screening of gold nanoparticle synthesis parameters in droplet microfluidics

IF 1.8 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Mendeleev Communications Pub Date : 2024-11-01 DOI:10.1016/j.mencom.2024.10.005

Nikita V. Egil , Alexander D. Zagrebaev , Pavel V. Medvedev , Alexander A. Alexandrov , Anton P. Bagliy , Sergey V. Chapek , Alexander A. Guda , Alexander V. Soldatov

引用次数: 0

Abstract

A 3D printed microreactor and UV-VIS spectral diagnostic system were adapted for an automatic protocol for screening parameters of citrate-based droplet synthesis of gold nanoparticles. Using this system, 27 combinations of synthesis parameters were screened within an hour and data were collected from more than 1000 individual droplets with nanoparticles. The developed system allows both filtering the spectra of target droplets and conducting a comprehensive multivariate analysis of all key descriptors.

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液滴微流体中金纳米颗粒合成参数的高通量筛选

采用3D打印微反应器和紫外可见光谱诊断系统，自动筛选柠檬酸盐基微滴合成金纳米颗粒的参数。使用该系统，在一小时内筛选了27种合成参数组合，并从1000多个含有纳米颗粒的单个液滴中收集了数据。开发的系统既可以过滤目标液滴的光谱，又可以对所有关键描述符进行全面的多变量分析。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Mendeleev Communications 化学-化学综合

CiteScore

3.00

自引率

21.10%

发文量

226

审稿时长

4-8 weeks

期刊介绍： Mendeleev Communications is the journal of the Russian Academy of Sciences, launched jointly by the Academy of Sciences of the USSR and the Royal Society of Chemistry (United Kingdom) in 1991. Starting from 1st January 2007, Elsevier is the new publishing partner of Mendeleev Communications. Mendeleev Communications publishes short communications in chemistry. The journal primarily features papers from the Russian Federation and the other states of the former USSR. However, it also includes papers by authors from other parts of the world. Mendeleev Communications is not a translated journal, but instead is published directly in English. The International Editorial Board is composed of eminent scientists who provide advice on refereeing policy.