A non-enzymatic electrochemical sensor based on zinc oxide/reduced graphene oxide (ZnO/rGO) nanocomposite for effective detection of urea

IF 3.9 3区材料科学 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY

Materials Science and Engineering: B Pub Date : 2024-11-29 DOI:10.1016/j.mseb.2024.117862

S.M. Aparna, R.B. Rakhi

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Abstract

Monitoring urea levels is essential for detecting water and soil pollution and diagnosing urea cycle disorder-related diseases. The present study addresses the need for an efficient, accurate, and cost-effective detection method by developing an electrochemical sensor using ZnO/rGO nanocomposites. The sensor’s performance is evaluated through cyclic voltammetry, differential pulse voltammetry, and amperometry, with different weight ratios of ZnO and rGO (3:1, 1:1, and 1:3). The results show that the ZnO/rGO (1:1) nanocomposite modified electrode exhibits remarkable sensitivity (850.15 μA^-1 mM⁻¹ cm⁻²), a low limit of detection (0.07 μM), excellent selectivity, and long-term stability for urea detection. Developed sensor leverages the advantages of electrochemical sensing, including simplicity, rapid response, high sensitivity, and good selectivity, making it a promising solution for environmental monitoring and medical diagnostics.

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一种基于氧化锌/还原氧化石墨烯（ZnO/rGO）纳米复合材料的无酶电化学传感器，用于有效检测尿素

监测尿素水平对于检测水和土壤污染以及诊断尿素循环紊乱相关疾病至关重要。本研究通过开发一种使用ZnO/rGO纳米复合材料的电化学传感器来解决对高效、准确和经济的检测方法的需求。通过循环伏安法、差分脉冲伏安法和安培法，在氧化锌和氧化石墨烯的重量比（3:1、1:1和1:3）下，对传感器的性能进行了评价。结果表明：ZnO/rGO（1:1）纳米复合修饰电极对尿素检测具有显著的灵敏度（850.15 μA-1 mM−1 cm−2）、低检出限（0.07 μM）、良好的选择性和长期稳定性。该传感器利用电化学传感的简单、快速、灵敏度高、选择性好等优点，为环境监测和医疗诊断提供了一种很有前景的解决方案。

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来源期刊

Materials Science and Engineering: B 工程技术-材料科学：综合

CiteScore

5.60

自引率

2.80%

发文量

481

审稿时长

3.5 months

期刊介绍： The journal provides an international medium for the publication of theoretical and experimental studies and reviews related to the electronic, electrochemical, ionic, magnetic, optical, and biosensing properties of solid state materials in bulk, thin film and particulate forms. Papers dealing with synthesis, processing, characterization, structure, physical properties and computational aspects of nano-crystalline, crystalline, amorphous and glassy forms of ceramics, semiconductors, layered insertion compounds, low-dimensional compounds and systems, fast-ion conductors, polymers and dielectrics are viewed as suitable for publication. Articles focused on nano-structured aspects of these advanced solid-state materials will also be considered suitable.