Biomineralization in magnetotactic bacteria: From diversity to molecular discovery-based applications.

IF 7.5 1区生物学 Q1 CELL BIOLOGY

Cell reports Pub Date : 2024-11-26 DOI:10.1016/j.celrep.2024.114995

Juan Wan, Runjia Ji, Jia Liu, Kun Ma, Yongxin Pan, Wei Lin

引用次数: 0

Abstract

The synthesis of magnetic nanoparticles (Fe₃O₄ or Fe₃S₄) within the membrane-bound organelles known as magnetosomes in magnetotactic bacteria (MTB) is a remarkable example of microbial-controlled biomineralization. Studying MTB biomineralization is crucial not only for understanding the origin and evolution of magnetoreception and bacterial organelles but also for advancing biotechnological and biomedical applications of MTB cells and magnetosomes. After decades of research, MTB have revealed unexpected diversity and complexity. The mechanisms underlying magnetosome biomineralization in MTB have been continuously documented using a few model MTB strains. In this review, we provide an overview of recent findings related to MTB diversity and focus primarily on the current understanding of magnetosome biosynthesis. Additionally, we summarize the growing biotechnological and biomedical applications derived from molecular studies of MTB and their magnetosomes.

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磁性细菌的生物矿化：从多样性到基于分子发现的应用。

磁传导细菌（MTB）在被称为磁小体的膜结合细胞器内合成磁性纳米粒子（Fe3O4 或 Fe3S4），是微生物控制生物矿化的一个杰出范例。研究 MTB 的生物矿化不仅对了解磁感应和细菌细胞器的起源和进化至关重要，而且对推动 MTB 细胞和磁小体的生物技术和生物医学应用也至关重要。经过几十年的研究，MTB 揭示了意想不到的多样性和复杂性。人们利用一些 MTB 模式菌株不断记录 MTB 磁小体生物矿化的基本机制。在这篇综述中，我们概述了与 MTB 多样性相关的最新发现，并主要关注目前对磁小体生物合成的理解。此外，我们还总结了 MTB 及其磁小体的分子研究带来的不断增长的生物技术和生物医学应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cell reports CELL BIOLOGY-

CiteScore

13.80

自引率

1.10%

发文量

1305

审稿时长

77 days

期刊介绍： Cell Reports publishes high-quality research across the life sciences and focuses on new biological insight as its primary criterion for publication. The journal offers three primary article types: Reports, which are shorter single-point articles, research articles, which are longer and provide deeper mechanistic insights, and resources, which highlight significant technical advances or major informational datasets that contribute to biological advances. Reviews covering recent literature in emerging and active fields are also accepted. The Cell Reports Portfolio includes gold open-access journals that cover life, medical, and physical sciences, and its mission is to make cutting-edge research and methodologies available to a wide readership. The journal's professional in-house editors work closely with authors, reviewers, and the scientific advisory board, which consists of current and future leaders in their respective fields. The advisory board guides the scope, content, and quality of the journal, but editorial decisions are independently made by the in-house scientific editors of Cell Reports.