Sympathetic NPY boosts thermogenic adipocytes.

IF 4.2 2区医学 Q1 ENDOCRINOLOGY & METABOLISM

American journal of physiology. Endocrinology and metabolism Pub Date : 2025-01-01 Epub Date: 2024-11-28 DOI:10.1152/ajpendo.00377.2024

Luis Leon-Mercado, Laurent Gautron

引用次数: 0

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交感神经 NPY 促进生热脂肪细胞的生长

人们对外周神经肽 Y（NPY）在调节能量平衡中的作用知之甚少。Zhu 等人最近在《自然》杂志上发表的一项研究表明，交感神经末梢在脂肪组织中释放的 NPY 能刺激生热脂肪细胞的增殖。该研究结果可能会对交感神经 NPY 与肥胖之间的联系机制带来新的启示。

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来源期刊

American journal of physiology. Endocrinology and metabolism 医学-内分泌学与代谢

CiteScore

9.80

自引率

0.00%

发文量

审稿时长

1 months

期刊介绍： The American Journal of Physiology-Endocrinology and Metabolism publishes original, mechanistic studies on the physiology of endocrine and metabolic systems. Physiological, cellular, and molecular studies in whole animals or humans will be considered. Specific themes include, but are not limited to, mechanisms of hormone and growth factor action; hormonal and nutritional regulation of metabolism, inflammation, microbiome and energy balance; integrative organ cross talk; paracrine and autocrine control of endocrine cells; function and activation of hormone receptors; endocrine or metabolic control of channels, transporters, and membrane function; temporal analysis of hormone secretion and metabolism; and mathematical/kinetic modeling of metabolism. Novel molecular, immunological, or biophysical studies of hormone action are also welcome.