Age Considerations in the Invasive Management of Acute Coronary Syndromes.

US cardiology Pub Date : 2022-05-25 eCollection Date: 2022-01-01 DOI:10.15420/usc.2021.29
Mansi Oberoi, Nitesh Ainani, J Dawn Abbott, Mamas A Mamas, Poonam Velagapudi
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Abstract

The elderly constitute a major proportion of patients admitted with acute coronary syndrome (ACS) in the US. Due to pre-existing comorbidities, frailty, and increased risk ofcomplications from medical and invasive therapies, management ofACS in the elderly population poses challenges. In patients with ST-elevation MI, urgent revascularization with primary percutaneous coronary intervention remains the standard of care irrespective of age. However, an early invasive approach in elderly patients with non-ST-elevation MI is based on individual evaluation of risks versus benefits. In this review, the authors discuss the unique characteristics of elderly patients presenting with ACS, specific geriatric conditions that need to be considered while making treatment decisions in these situations, and available evidence, current guidelines, and future directions for invasive management of elderly patients with ACS.

急性冠状动脉综合征侵入性治疗中的年龄因素。
在美国,老年人在急性冠状动脉综合征(ACS)入院患者中占很大比例。由于原有的合并症、身体虚弱以及医疗和侵入性疗法引起并发症的风险增加,老年人群的急性冠状动脉综合征管理面临着挑战。对于 ST 段抬高型心肌梗死患者,无论年龄大小,通过经皮冠状动脉介入治疗进行紧急血运重建仍是治疗标准。然而,对于非 ST 段抬高型心肌梗死的老年患者,早期有创介入治疗是基于对风险与收益的个体评估。在这篇综述中,作者讨论了急性冠状动脉综合征老年患者的独特特征、在这些情况下做出治疗决定时需要考虑的特定老年疾病,以及急性冠状动脉综合征老年患者有创治疗的现有证据、现行指南和未来方向。
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