Drosophila melanogaster c306 GAL4 is not specific to ovarian cells.

microPublication biology Pub Date : 2024-11-11 eCollection Date: 2024-01-01 DOI:10.17912/micropub.biology.001383
Ashley C Goll, Kaden H Bex, Tina L Tootle
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Abstract

A widely used genetic tool in Drosophila melanogaster is the GAL4/UAS system. This bipartite system allows for tissue and cell-specific expression and is used for both overexpression and RNA interference (RNAi) knockdown studies. Here we provide evidence that c306 GAL4 expression is not restricted to somatic ovarian cells but is also expressed in cells giving rise to adult bristles. Future work is needed to fully define the cell-specific expression pattern c306 GAL4.

黑腹果蝇 c306 GAL4 对卵巢细胞没有特异性。
黑腹果蝇广泛使用的遗传工具是 GAL4/UAS 系统。这种双元系统可实现组织和细胞特异性表达,并可用于过表达和 RNA 干扰(RNAi)敲除研究。在这里,我们提供的证据表明,c306 GAL4 的表达并不局限于体卵巢细胞,它也在产生成刚毛的细胞中表达。要完全确定c306 GAL4的细胞特异性表达模式,还需要未来的工作。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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