Current Trends in HIV Infection in the Republic of Crimea.

IF 3.8 3区 医学 Q2 VIROLOGY
Viruses-Basel Pub Date : 2024-10-31 DOI:10.3390/v16111716
Aleksei Mazus, Anastasiia Antonova, Ruslan Adgamov, Daria Ogarkova, Anna Kuznetsova, Andrei Pochtovyi, Elena Tsyganova, Vladimir Zlobin, Vladimir Gushchin, Andrei Plutnitskii, Aleksandr Gintsburg
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Abstract

The aim of this study was to analyse the trends in HIV infection, including diagnostic ones, in the Republic of Crimea in the period of 2014-2023. The source of data for this study was various statistical forms and reports. The findings revealed a significant downward trend in HIV incidence and a significant upward trend in HIV prevalence. The mortality rate was stable. The coverage of HIV testing and antiretroviral therapy increased over time. The number of patients with a suppressed viral load in the Republic fluctuated in different years of observation and reached 81% in 2023. In the second part of this study, we analysed the demographic and clinical laboratory characteristics of newly diagnosed patients with HIV. A predominance of men was noted. The proportion of injection drug users (IDUs) decreased, and the proportion of new HIV infection cases through heterosexual contacts increased. An increase in the median age of patients was also noted. Analysis of CD4 cell counts revealed significant differences between subgroups by gender, age, and route of infection. The longest time to disease detection was typical for IDUs. A comprehensive assessment of HIV infection trends in Crimea allows us to evaluate the effectiveness of measures and decisions taken on the issue of HIV infection.

克里米亚共和国艾滋病毒感染的当前趋势。
本研究旨在分析 2014-2023 年期间克里米亚共和国艾滋病毒感染的趋势,包括诊断趋势。本研究的数据来源于各种统计表格和报告。研究结果显示,艾滋病毒感染率呈明显下降趋势,艾滋病毒流行率呈明显上升趋势。死亡率保持稳定。随着时间的推移,艾滋病毒检测和抗逆转录病毒疗法的覆盖率有所提高。共和国病毒载量得到抑制的患者人数在不同的观察年份有所波动,2023 年达到 81%。在本研究的第二部分,我们分析了新诊断出的艾滋病毒感染者的人口统计学和临床实验室特征。我们注意到男性占多数。注射毒品使用者(IDUs)的比例有所下降,而通过异性接触感染艾滋病毒的新病例比例有所上升。患者的年龄中位数也有所上升。对 CD4 细胞计数的分析表明,不同性别、年龄和感染途径的亚组之间存在显著差异。注射吸毒者发现疾病的时间最长。对克里米亚艾滋病毒感染趋势的全面评估使我们能够评价针对艾滋病毒感染问题所采取的措施和决定的有效性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Viruses-Basel
Viruses-Basel VIROLOGY-
CiteScore
7.30
自引率
12.80%
发文量
2445
审稿时长
1 months
期刊介绍: Viruses (ISSN 1999-4915) is an open access journal which provides an advanced forum for studies of viruses. It publishes reviews, regular research papers, communications, conference reports and short notes. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. We also encourage the publication of timely reviews and commentaries on topics of interest to the virology community and feature highlights from the virology literature in the ''News and Views'' section. Electronic files or software regarding the full details of the calculation and experimental procedure, if unable to be published in a normal way, can be deposited as supplementary material.
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