How Epstein Barr Virus Causes Lymphomas.

IF 3.8 3区医学 Q2 VIROLOGY

Viruses-Basel Pub Date : 2024-11-06 DOI:10.3390/v16111744

Ya-Fang Chiu, Khongpon Ponlachantra, Bill Sugden

引用次数: 0

Abstract

Since Epstein-Barr Virus (EBV) was isolated 60 years ago, it has been studied clinically, epidemiologically, immunologically, and molecularly in the ensuing years. These combined studies allow a broad mechanistic understanding of how this ubiquitous human pathogen which infects more than 90% of adults can rarely cause multiple types of lymphomas. We survey these findings to provide a coherent description of its oncogenesis.

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Epstein Barr 病毒如何导致淋巴瘤？

自 60 年前分离出爱泼斯坦-巴氏病毒（EBV）以来，人们一直在对它进行临床学、流行病学、免疫学和分子学研究。通过这些综合研究，我们对这种无处不在、感染 90% 以上成年人的人类病原体如何罕见地引发多种类型的淋巴瘤有了广泛的机理认识。我们将对这些研究结果进行综述，以便对其肿瘤发生过程进行连贯的描述。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Viruses-Basel VIROLOGY-

CiteScore

7.30

自引率

12.80%

发文量

2445

审稿时长

1 months

期刊介绍： Viruses (ISSN 1999-4915) is an open access journal which provides an advanced forum for studies of viruses. It publishes reviews, regular research papers, communications, conference reports and short notes. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. We also encourage the publication of timely reviews and commentaries on topics of interest to the virology community and feature highlights from the virology literature in the ''News and Views'' section. Electronic files or software regarding the full details of the calculation and experimental procedure, if unable to be published in a normal way, can be deposited as supplementary material.