Lavel C Moonga, Jones Chipinga, John P Collins, Vishal Kapoor, Ngonda Saasa, King S Nalubamba, Bernard M Hang'ombe, Boniface Namangala, Tapiwa Lundu, Xiang-Jun Lu, Samuel Yingst, J Kenneth Wickiser, Thomas Briese
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引用次数: 0
Abstract
We utilized a pan-viral capture sequencing assay, VirCapSeq-VERT, to assess viral diversity in rodents from the Eastern Province of Zambia as a model for pre-pandemic viral reservoir surveillance. We report rodent adeno-, parvo-, paramyxo-, and picornaviruses that represent novel species or isolates, including murine adenovirus 4, two additional species in the genus Chaphamaparvovirus, two paramyxoviruses distantly related to unclassified viruses in the genus Jeilongvirus, and the first Aichivirus A sequence identified from rodents in Africa. Our results emphasize the importance of rodents as a reservoir for potential zoonotic viruses.
我们利用泛病毒捕获测序法(VirCapSeq-VERT)评估了赞比亚东部省啮齿动物的病毒多样性,并将其作为流行前病毒库监测的模型。我们报告的啮齿动物腺病毒、巴氏杆菌、副粘病毒和皮卡病毒代表了新的物种或分离株,包括小鼠腺病毒 4、查帕病毒属的另外两个物种、两种与杰隆病毒属未分类病毒有远缘关系的副粘病毒,以及首次从非洲啮齿动物中鉴定出的 Aichivirus A 序列。我们的研究结果强调了啮齿动物作为潜在人畜共患病病毒储库的重要性。
期刊介绍:
Viruses (ISSN 1999-4915) is an open access journal which provides an advanced forum for studies of viruses. It publishes reviews, regular research papers, communications, conference reports and short notes. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. We also encourage the publication of timely reviews and commentaries on topics of interest to the virology community and feature highlights from the virology literature in the ''News and Views'' section. Electronic files or software regarding the full details of the calculation and experimental procedure, if unable to be published in a normal way, can be deposited as supplementary material.