Hyun Jin Ahn, Francesco Bruno, Jeehoon Kang, Doyeon Hwang, Han-Mo Yang, Jung-Kyu Han, Leonardo De Luca, Ovidio de Filippo, Alessio Mattesini, Kyung Woo Park, Alessandra Truffa, Wojciech Wanha, Young Bin Song, Sebastiano Gili, Woo Jung Chun, Gerard Helft, Seung-Ho Hur, Bernardo Cortese, Seung Hwan Han, Javier Escaned, Alaide Chieffo, Ki Hong Choi, Guglielmo Gallone, Joon-Hyung Doh, Gaetano De Ferrari, Soon-Jun Hong, Giorgio Quadri, Chang-Wook Nam, Hyeon-Cheol Gwon, Hyo-Soo Kim, Fabrizio D'Ascenzo, Bon-Kwon Koo
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引用次数: 0
Abstract
Background and objectives: The risk profiles, procedural characteristics, and clinical outcomes for women undergoing bifurcation percutaneous coronary intervention (PCI) are not well defined compared to those in men.
Methods: COronary BIfurcation Stenting III (COBIS III) is a multicenter, real-world registry of 2,648 patients with bifurcation lesions treated with second-generation drug-eluting stents. We compared the angiographic and procedural characteristics and clinical outcomes based on sex. The primary outcome was 5-year target lesion failure (TLF), a composite of cardiac death, myocardial infarction, and target lesion revascularization.
Results: Women (n=635, 24%) were older, had hypertension and diabetes more often, and had smaller main vessel and side branch reference diameters than men. The pre- and post-PCI angiographic percentage diameter stenoses of the main vessel and side branch were comparable between women and men. There were no differences in procedural characteristics between the sexes. Women and men had a similar risk of TLF (6.3% vs. 7.1%, p=0.63) as well as its individual components and sex was not an independent predictor of TLF. This finding was consistent in the left main and 2 stenting subgroups.
Conclusions: In patients undergoing bifurcation PCI, sex was not an independent predictor of adverse outcome.
期刊介绍：
Korean Circulation Journal is the official journal of the Korean Society of Cardiology, the Korean Pediatric Heart Society, the Korean Society of Interventional Cardiology, and the Korean Society of Heart Failure. Abbreviated title is ''Korean Circ J''.
Korean Circulation Journal, established in 1971, is a professional, peer-reviewed journal covering all aspects of cardiovascular medicine, including original articles of basic research and clinical findings, review articles, editorials, images in cardiovascular medicine, and letters to the editor. Korean Circulation Journal is published monthly in English and publishes scientific and state-of-the-art clinical articles aimed at improving human health in general and contributing to the treatment and prevention of cardiovascular diseases in particular.
The journal is published on the official website (https://e-kcj.org). It is indexed in PubMed, PubMed Central, Science Citation Index Expanded (SCIE, Web of Science), Scopus, EMBASE, Chemical Abstracts Service (CAS), Google Scholar, KoreaMed, KoreaMed Synapse and KoMCI, and easily available to wide international researchers
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