A Comprehensive Review on Bioactive Molecules and Advanced Microorganism Management Technologies.

IF 2.8 3区生物学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY

Current Issues in Molecular Biology Pub Date : 2024-11-20 DOI:10.3390/cimb46110789

Adil Farooq Wali, Sirajunisa Talath, Sathvik B Sridhar, Javedh Shareef, Manjunatha Goud, Imran Rashid Rangraze, Nowar Nizar Alaani, Omnia Ibrahim Mohamed

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引用次数: 0

Abstract

The advent of new strains of resistant microbes and the concomitant growth in multidrug resistance have made antimicrobial resistance an urgent public health concern. New antimicrobials are desperately needed to boost the success rates of treating infectious diseases and save lives. There are many intriguing biomolecules with antibacterial action, which are mostly unexplored in microorganisms. This review article describes the importance of natural compounds against microorganisms using advanced techniques to protect individuals from diseases. We have conducted an extensive literature review using databases such as SCOPUS, SCI, PUBMED, ScienceDirect, and Medline to gather relevant information. Our review covers various microorganism sources for antimicrobials, antifungal drugs, micro-culturing techniques, and microbial-based microsystems' applications. Every kind of higher trophic life depends on microorganisms for sustenance. The unseen majority is essential to understanding how humans and other living forms can survive anthropogenic climate change. The article discusses antimicrobial substances and the latest techniques and strategies for developing effective treatments. Novel model systems and cutting-edge biomolecular and computational methodologies could help researchers enhance antimicrobial resistance by completely capitalizing on lead antimicrobials.

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生物活性分子和先进微生物管理技术综述。

新的抗药性微生物菌株的出现以及随之而来的多重耐药性的增长，使抗菌药耐药性成为一个紧迫的公共卫生问题。为了提高治疗传染病的成功率和挽救生命，我们迫切需要新的抗菌药物。有许多具有抗菌作用的生物大分子令人感兴趣，但它们在微生物中大多尚未被开发。这篇综述文章介绍了天然化合物利用先进技术抗击微生物以保护人类免受疾病侵害的重要性。我们利用 SCOPUS、SCI、PUBMED、ScienceDirect 和 Medline 等数据库进行了广泛的文献综述，以收集相关信息。我们的综述涵盖了抗菌剂、抗真菌药物、微培养技术和基于微生物的微系统应用的各种微生物来源。每一种高等营养生物都依赖微生物维持生命。要了解人类和其他生物如何在人为气候变化中生存，看不见的大多数微生物至关重要。文章讨论了抗菌物质以及开发有效治疗方法的最新技术和策略。新颖的模型系统以及尖端的生物分子和计算方法可以帮助研究人员通过完全利用先导抗菌素来增强抗菌能力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Issues in Molecular Biology 生物-生化研究方法

CiteScore

2.90

自引率

3.20%

发文量

380

审稿时长

>12 weeks

期刊介绍： Current Issues in Molecular Biology (CIMB) is a peer-reviewed journal publishing review articles and minireviews in all areas of molecular biology and microbiology. Submitted articles are subject to an Article Processing Charge (APC) and are open access immediately upon publication. All manuscripts undergo a peer-review process.