Use of non-barrier contraceptives among women with human immunodeficiency virus; a nationwide, matched cohort study.

IF 3.4 2区 医学 Q3 IMMUNOLOGY
AIDS Pub Date : 2024-11-26 DOI:10.1097/QAD.0000000000004067
Fie W Paulsen, Malte M Tetens, Jan Gerstoft, Gitte Kronborg, Isik S Johansen, Carsten S Larsen, Lothar Wiese, Michael Dalager-Pedersen, Suzanne Lunding, Lars N Nielsen, Anja B Pinborg, Nina Weis, Lars H Omland, Niels Obel, Anne-Mette Lebech
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引用次数: 0

Abstract

Objective: To investigate the use of non-barrier contraceptives among women with HIV (WWH) compared to women from the general population (WGP) in Denmark.

Design: Nationwide population-based matched cohort study.

Methods: We included WWH aged 16-50, treated at an HIV specialized clinic, and included in The Danish HIV Cohort Study between 1995-2021 and an age-matched comparison cohort of WGP. We examined use of hormonal contraception (HC), intrauterine devices (IUD), and sterilization from 10 years before to 20 years after study inclusion. Additionally, we calculated age-standardized proportions and incidences over calendar time.

Results: We included 1,720 WWH and 17,720 WGP. Median age was 33 years and almost half of WWH had African origin (41%). Non-barrier contraceptive use was lower among WWH (8.5%) compared to WGP (32.1%) at study inclusion. Before and after inclusion, WWH had nearly half the non-barrier contraceptive use of WGP, with notably lower HC and IUD use. Initially, fewer WWH were sterilized, but five years after inclusion, sterilization became the preferred method among WWH. HC use increased among WWH after 2010 but decreased among WGP after 2005. IUD use increased among both groups during 1995-2021 but remained lower among WWH. Incidence of sterilizations remained stable in both groups.

Conclusion: Use of non-barrier contraceptives was lower among WWH compared to WGP. For WWH, sterilization became the preferred non-barrier method few years after study inclusion. HC and IUD use increased among WWH after 2010 but remained lower than for WGP. Improved contraceptive counseling is recommended to support reproductive health among WWH.

人类免疫缺陷病毒感染妇女使用无屏障避孕药具的情况;一项全国范围的匹配队列研究。
目的调查丹麦感染艾滋病毒妇女(WWH)与普通人群妇女(WGP)使用无屏障避孕药具的情况:设计:基于全国人口的匹配队列研究:我们纳入了年龄在 16-50 岁、在艾滋病专科门诊接受治疗、1995-2021 年间被纳入丹麦艾滋病队列研究(The Danish HIV Cohort Study)的女性艾滋病病毒感染者(WWH),以及年龄匹配的女性艾滋病病毒感染者(WGP)对比队列。我们调查了纳入研究前 10 年至纳入研究后 20 年间激素避孕 (HC)、宫内节育器 (IUD) 和绝育的使用情况。此外,我们还计算了日历时间内的年龄标准化比例和发病率:我们纳入了 1,720 名妇女保健工作者和 17,720 名妇女一般保健人员。中位年龄为 33 岁,近一半的妇女保健工作者来自非洲(41%)。在纳入研究时,WWH(8.5%)与 WGP(32.1%)相比使用无屏障避孕药具的比例较低。在纳入研究之前和之后,WWH 的非阻隔性避孕药具使用率几乎是 WGP 的一半,而 HC 和宫内节育器的使用率则明显较低。最初,接受绝育手术的 WWH 较少,但在纳入研究五年后,绝育成为 WWH 的首选方法。2010 年后,WWH 使用 HC 的情况有所增加,但 2005 年后,WGP 使用 HC 的情况有所减少。1995-2021 年间,两个群体中宫内节育器的使用率都有所上升,但 WWH 的使用率仍然较低。两个群体的绝育率保持稳定:结论:与 WGP 相比,WWH 使用无屏障避孕药具的比例较低。对于 WWH 来说,绝育成为研究纳入几年后的首选非屏障避孕方法。2010 年后,WWH 使用 HC 和宫内节育器的人数有所增加,但仍低于 WGP。建议改进避孕咨询,以支持妇女和保健工作者的生殖健康。
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来源期刊
AIDS
AIDS 医学-病毒学
CiteScore
5.90
自引率
5.30%
发文量
478
审稿时长
3 months
期刊介绍: ​​​​​​​​​​​​​​​​​Publishing the very latest ground breaking research on HIV and AIDS. Read by all the top clinicians and researchers, AIDS has the highest impact of all AIDS-related journals. With 18 issues per year, AIDS guarantees the authoritative presentation of significant advances. The Editors, themselves noted international experts who know the demands of your work, are committed to making AIDS the most distinguished and innovative journal in the field. Submitted articles undergo a preliminary review by the editor. Some articles may be returned to authors without further consideration. Those being considered for publication will undergo further assessment and peer-review by the editors and those invited to do so from a reviewer pool.
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