Hospitalization due to pneumococcal disease in the Unified Health System in Brazil: A retrospective analysis of administrative data

IF 3 4区医学 Q2 INFECTIOUS DISEASES

Brazilian Journal of Infectious Diseases Pub Date : 2024-11-27 DOI:10.1016/j.bjid.2024.104482

Daniela V. Pachito , Mauricio Longato , Guilherme Cordeiro , Paulo H.R.F. Almeida , Ricardo Macarini Ferreira , Ana Paula N. Burian

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引用次数: 0

Abstract

Introduction

Community-Acquired Pneumonia (CAP) caused by pneumococcus and Invasive Pneumococcal Disease (IPD) pose a substantial economic burden on health systems. The objective of the present study is to explore hospitalization costs of pneumococcal disease in the public health system in Brazil, the Unified Health System.

Methods

Retrospective analysis of administrative data on hospitalized cases of pneumococcal disease from January 2019 to July 2023. Hospitalization cases recorded with ICD-10 codes of CAP due to S. pneumoniae and IPD were retrieved from DATASUS, the inpatient information system of the Unified Health System in Brazil. Costs were converted to US dollars by Using Purchasing Power Parity (USD-PPP). Absolute number of hospitalizations, costs of hospitalizations and healthcare resource utilization were presented descriptively. The annual cost estimate was calculated. Differences in costs by type of clinical presentation and age group were assessed. Factors associated with higher costs were explored by multiple linear regression models.

Results

A total of 22,498 hospitalization episodes were analyzed. Total cost of hospitalizations was USD-PPP 13,958,959 (BRL 34,659,578) with an annual mean estimate of USD-PPP 3,045,591 (BRL 7,562,090). Cost per hospitalization episode was significantly higher for meningitis, followed by septicemia, CAP and arthritis, with median values ranging from USD-PPP 190.93 to 615.14 (BRL 476.20 to 1529.02). (Kruskal-Wallis χ² = 6473, df = 3, p-value < 0.0001). Costs were significantly higher among individuals aged 60-years and older. (Kruskal-Wallis test; χ² = 773.53; df = 2, p-value < 0.0001). There were differences in age at hospitalization, length of stay, and ICU utilization among types of clinical presentations.

Conclusions

Our findings reveal the economic burden associated with pneumococcal disease in the Unified Health System in Brazil. Hospitalization costs were higher for cases of meningitis and among individuals aged 60-years and above.

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巴西统一卫生系统中因肺炎球菌疾病住院的情况：行政数据的回顾性分析

引言肺炎球菌引起的社区获得性肺炎 (CAP) 和侵袭性肺炎球菌疾病 (IPD) 给卫生系统造成了巨大的经济负担。本研究旨在探讨巴西公共卫生系统（统一卫生系统）中肺炎球菌疾病的住院费用。方法回顾性分析 2019 年 1 月至 2023 年 7 月肺炎球菌疾病住院病例的管理数据。从巴西统一卫生系统（Unified Health System）的住院病人信息系统 DATASUS 中检索记录了 ICD-10 代码为肺炎链球菌引起的 CAP 和 IPD 的住院病例。费用按购买力平价（USD-PPP）换算成美元。对住院绝对人数、住院费用和医疗资源利用情况进行了描述性说明。计算了年度成本估算。评估了不同临床表现类型和年龄组的成本差异。通过多元线性回归模型探讨了与较高费用相关的因素。住院总费用为13,958,959美元（34,659,578巴西雷亚尔），年平均费用估计为3,045,591美元（7,562,090巴西雷亚尔）。脑膜炎的每次住院费用明显较高，其次是败血症、CAP 和关节炎，中值范围为 190.93 至 615.14 美元（476.20 至 1529.02 巴西雷亚尔）。(Kruskal-Wallis χ2 = 6473，df = 3，p-value < 0.0001）。60 岁及以上人群的费用明显更高。(Kruskal-Wallis 检验；χ2 = 773.53；df = 2，P 值为 0.0001）。结论我们的研究结果揭示了巴西统一卫生系统中与肺炎球菌疾病相关的经济负担。脑膜炎病例和 60 岁及以上人群的住院费用较高。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Brazilian Journal of Infectious Diseases 医学-传染病学

CiteScore

5.50

自引率

0.00%

发文量

925

审稿时长

41 days

期刊介绍： The Brazilian Journal of Infectious Diseases is the official publication of the Brazilian Society of Infectious Diseases (SBI). It aims to publish relevant articles in the broadest sense on all aspects of microbiology, infectious diseases and immune response to infectious agents. The BJID is a bimonthly publication and one of the most influential journals in its field in Brazil and Latin America with a high impact factor, since its inception it has garnered a growing share of the publishing market.