Ullmann coupling reaction of dihalobenzenes and malononitrile-heterocumulene adducts under ultrasound-irradiation

IF 2.1 3区化学 Q2 CHEMISTRY, ORGANIC

Tetrahedron Pub Date : 2024-11-16 DOI:10.1016/j.tet.2024.134381

Manijeh Nematpour

引用次数: 0

Abstract

In this study, various benzothiazoles, benzoxazoles, and benzo[1,3]-dithiols derivatives with good yields were obtained using the Ullmann coupling reaction of dihalobenzenes and malononitrile-heterocumulene adducts in the vicinity of copper catalyst, Cs₂CO₃ as a base under ultrasound irradiation. The use of the popular sonochemical method, short reaction time, simple and available raw materials, mild catalytic copper reaction conditions, simple purification, and good efficiency are some of the notable characteristics of this protocol.

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超声辐照下二卤苯和丙二腈-杂茂烯加合物的乌尔曼偶联反应

本研究在超声辐照下，以铜为催化剂，Cs2CO3 为碱，利用二卤苯和丙二腈-杂茂烯加合物在铜催化剂附近发生的乌尔曼偶联反应，获得了多种苯并噻唑、苯并恶唑和苯并[1,3]-二硫醇衍生物，且收率良好。该方案采用流行的超声化学方法，反应时间短，原料简单易得，铜催化反应条件温和，纯化简单，效率高。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Tetrahedron 化学-有机化学

CiteScore

3.90

自引率

4.80%

发文量

439

审稿时长

34 days

期刊介绍： Tetrahedron publishes full accounts of research having outstanding significance in the broad field of organic chemistry and its related disciplines, such as organic materials and bio-organic chemistry. Regular papers in Tetrahedron are expected to represent detailed accounts of an original study having substantially greater scope and details than that found in a communication, as published in Tetrahedron Letters. Tetrahedron also publishes thematic collections of papers as special issues and ''Reports'', commissioned in-depth reviews providing a comprehensive overview of a research area.