Mastitis granulomatosa con buena respuesta a baricitinib

Abstract

Granulomatous mastitis is a benign disease of the breast, characterized by the formation of granulomas in the lobules. It occurs in women of reproductive age, commonly with a history of breastfeeding. It is manifested by the formation of abscesses or tumors. For the diagnosis, a biopsy is required and to rule out, in addition to infectious processes, autoimmune diseases. Treatment is controversial, antimicrobials, steroids, immunosuppressants, biological therapy, and surgery have been used. We present the case of a 40-year-old woman with a typical picture of granulomatous mastitis, with failure to the usual therapeutic options, was managed with baricitinib, observing an excellent therapeutic response. There are insufficient data to recommend the use of baricitinib, but it could be considered in the event of standard treatment failure.