A Macrocycle-Mediated Protein Cage

IF 5.1 Q1 POLYMER SCIENCE

ACS Macro Letters Pub Date : 2024-11-26 DOI:10.1021/acsmacrolett.4c00656

Ronan J. Flood, Aurélien Thureau, Peter B. Crowley

引用次数: 0

Abstract

Engineered protein cages are of great interest considering their diverse applications in delivery and catalysis. Here, we describe macrocycle-triggered icosahedral cage assembly of a designed β-propeller. Cage assembly was evidenced by small-angle X-ray scattering and X-ray crystallography.

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大循环介导的蛋白质笼

考虑到工程蛋白质笼在传输和催化方面的多种应用，人们对其产生了浓厚的兴趣。在这里，我们描述了大环触发的二十面体笼子组装设计的 β-推进器。小角 X 射线散射和 X 射线晶体学证明了笼子的组装。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACS Macro Letters 化学-

CiteScore

10.40

自引率

3.40%

发文量

209

审稿时长

1 months

期刊介绍： ACS Macro Letters publishes research in all areas of contemporary soft matter science in which macromolecules play a key role, including nanotechnology, self-assembly, supramolecular chemistry, biomaterials, energy generation and storage, and renewable/sustainable materials. Submissions to ACS Macro Letters should justify clearly the rapid disclosure of the key elements of the study. The scope of the journal includes high-impact research of broad interest in all areas of polymer science and engineering, including cross-disciplinary research that interfaces with polymer science. With the launch of ACS Macro Letters, all Communications that were formerly published in Macromolecules and Biomacromolecules will be published as Letters in ACS Macro Letters.