Impact of Nonalcoholic Fatty Liver Disease on Weight Loss Outcomes After One Anastomosis Gastric Bypass.

IF 1.1 4区医学 Q3 SURGERY

Surgical Laparoscopy, Endoscopy & Percutaneous Techniques Pub Date : 2024-11-26 DOI:10.1097/SLE.0000000000001347

Rahmatullah Athar, Masoumeh Shahsavan, Shahab Shahabi, Abdolreza Pazouki, Farah A Husain, Mohammad Kermansaravi

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引用次数: 0

Abstract

Background: Obesity-associated nonalcoholic fatty liver disease (NAFLD) is a significant cause of chronic liver disease. Our study sought to investigate preoperative NAFLD and the effect at 6 months and 2 years after surgery of one anastomosis gastric bypass (OAGB) and its development 6 months after surgery regarding weight loss outcomes.

Materials and methods: A retrospective cohort study was conducted on patients with severe obesity who underwent primary OAGB at Hazrat-e-Rasool Hospital between March 2020 and June 2021. Preoperative assessments included abdominal ultrasound (US) for NAFLD grading, weight, and biochemical blood tests. Follow-up examinations were performed at 10 days and 1, 3, 6, 9, 12, and 24 months postsurgery, with subsequent US examinations at the 6-month follow-up.

Results: Two hundred thirty-one patients were included, with an average age of 40.3±10.5 years and a percentage of 78.4 women. Their mean weight and BMI were 131.2±26.8 and 48.8±8.5, respectively. Six-month grades of NAFLD showed that patients with grade 3 NAFLD had significantly lower TWL% compared with the lower grades. NAFLD grades improved in 72.3% of our patients, remained the same at 21.2%, and worsened at 6.5%. The 6-month TWL% was 28.4±4.3 in the no-change group, 28.4±5.3 for the improved group, and 25.2±14.6 in the worse group.

Conclusion: The severity and progression of NAFLD can significantly impact weight loss outcomes post-OAGB, highlighting the importance of monitoring and managing NAFLD in patients undergoing bariatric surgery.

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非酒精性脂肪肝对单次吻合胃旁路术后减肥效果的影响

背景：肥胖相关性非酒精性脂肪肝（NAFLD）是慢性肝病的一个重要原因。我们的研究旨在调查术前非酒精性脂肪肝、单吻合胃旁路术（OAGB）术后 6 个月和 2 年的影响，以及术后 6 个月非酒精性脂肪肝对减肥效果的影响：对2020年3月至2021年6月期间在Hazrat-e-Rasool医院接受初级OAGB手术的重度肥胖患者进行了一项回顾性队列研究。术前评估包括非酒精性脂肪肝分级的腹部超声波（US）、体重和生化血液检测。术后10天、1、3、6、9、12和24个月进行随访检查，6个月随访时再进行腹部超声检查：共纳入 231 名患者，平均年龄（40.3±10.5）岁，女性占 78.4%。他们的平均体重和体重指数分别为（131.2±26.8）和（48.8±8.5）。6个月的非酒精性脂肪肝等级显示，3级非酒精性脂肪肝患者的TWL%明显低于低级患者。72.3%的患者的非酒精性脂肪肝等级有所改善，21.2%的患者等级保持不变，6.5%的患者等级恶化。无变化组的6个月TWL%为28.4±4.3，改善组为28.4±5.3，恶化组为25.2±14.6：结论：非酒精性脂肪肝的严重程度和进展会严重影响OAGB术后的减重效果，因此在接受减肥手术的患者中监测和管理非酒精性脂肪肝非常重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Surgical Laparoscopy, Endoscopy & Percutaneous Techniques 医学-外科

CiteScore

2.00

自引率

10.00%

发文量

103

审稿时长

3-8 weeks

期刊介绍： Surgical Laparoscopy Endoscopy & Percutaneous Techniques is a primary source for peer-reviewed, original articles on the newest techniques and applications in operative laparoscopy and endoscopy. Its Editorial Board includes many of the surgeons who pioneered the use of these revolutionary techniques. The journal provides complete, timely, accurate, practical coverage of laparoscopic and endoscopic techniques and procedures; current clinical and basic science research; preoperative and postoperative patient management; complications in laparoscopic and endoscopic surgery; and new developments in instrumentation and technology.