A rare early gastric mixed neuroendocrine-non-neuroendocrine neoplasms misdignosed to early gastric cancer.

IF 2.7 4区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY
Pengwei Liu, Yan Zhang
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引用次数: 0

Abstract

Recently, mixed neuroendocrine-non-neuroendocrine neoplasms (MiNENs) have attracted more attention. However, early gastric MiNEN is uncommon, and there are rare reports on the characteristics of it. As its clinical and endoscopic features are resemble to early gastric cancer (EGC), it can be easily misdiagnosed. The purpose of this article is to elaborate the endoscopic and pathological characteristics of early gastric MiNEN, which is of great significance for distinguishing it from EGC. A 67-year-old male patient underwent EGD revealing a 0-IIc+IIa lesion on the lesser curvature of the lower stomach body. The biopsy pathology indicated the lesion was an EGC. Endoscopic submucosal dissection (ESD) was subsequently applied to remove the lesion. According to postoperative pathological, the lesion was diagnosed as early MiNEN (tubular adenocarcinoma 50%, neuroendocrine carcinoma 50%), pT1b (submucosa 600 μm), pUL (1), Ly (0), v (1), pHM0, pVM0. And after that, surgical resection were added. A follow-up CT scan and endoscopy performed six months later revealed no metastasis or recurrence. This case highlights that early gastric MiNEN could mimic ECG. We deemed that ME-NBI combined with pathological biopsy could contribute to the identification of early gastric MiNEN.

一种罕见的早期胃神经内分泌-非神经内分泌混合肿瘤被误诊为早期胃癌。
最近,神经内分泌-非神经内分泌混合瘤(MiNENs)引起了越来越多的关注。然而,早期胃米纳恩并不常见,有关其特征的报道也很少。由于其临床和内镜特征与早期胃癌(EGC)相似,很容易被误诊。本文旨在阐述早期胃 MiNEN 的内镜和病理特征,这对于将其与 EGC 相鉴别具有重要意义。一名 67 岁的男性患者接受了胃肠镜检查,发现胃体下部小弯处有 0-IIc+IIa 病变。活检病理结果显示病变为 EGC。随后,医生应用内镜黏膜下剥离术(ESD)切除了病灶。术后病理诊断为早期 MiNEN(管状腺癌 50%,神经内分泌癌 50%),pT1b(黏膜下 600 μm),pUL(1),Ly(0),v(1),pHM0,pVM0。之后,再进行手术切除。6 个月后进行的随访 CT 扫描和内镜检查显示没有转移或复发。该病例强调了早期胃米网状细胞瘤可模拟心电图。我们认为,ME-NBI 与病理活检相结合有助于识别早期胃米网状细胞癌。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
2.00
自引率
25.00%
发文量
400
审稿时长
6-12 weeks
期刊介绍: La Revista Española de Enfermedades Digestivas, Órgano Oficial de la Sociedad Española de Patología Digestiva (SEPD), Sociedad Española de Endoscopia Digestiva (SEED) y Asociación Española de Ecografía Digestiva (AEED), publica artículos originales, editoriales, revisiones, casos clínicos, cartas al director, imágenes en patología digestiva, y otros artículos especiales sobre todos los aspectos relativos a las enfermedades digestivas.
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