Viruses in the female lower reproductive tract: a systematic descriptive review of metagenomic investigations.

IF 7.8 1区生物学 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

npj Biofilms and Microbiomes Pub Date : 2024-11-25 DOI:10.1038/s41522-024-00613-6

Layla Honorato, Heuder Gustavo Oliveira Paião, Antonio Charlys da Costa, Tânia Regina Tozetto-Mendoza, Maria Cássia Mendes-Correa, Steven S Witkin

引用次数: 0

Abstract

The lower female reproductive tract (FRT) hosts a complex microbial environment, including eukaryotic and prokaryotic viruses (the virome), whose roles in health and disease are not fully understood. This review consolidates findings on FRT virome composition, revealing the presence of various viral families and noting significant gaps in knowledge. Understanding interactions between the virome, microbiome, and immune system will provide novel insights for preventing and managing lower genital tract disorders.

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女性下生殖道中的病毒：元基因组研究的系统描述性回顾。

女性下生殖道（FRT）寄居着复杂的微生物环境，包括真核和原核病毒（病毒体），它们在健康和疾病中的作用尚未完全明了。本综述整合了有关 FRT 病毒组组成的研究结果，揭示了各种病毒家族的存在，并指出了知识方面的重大差距。了解病毒组、微生物组和免疫系统之间的相互作用将为预防和治疗下生殖道疾病提供新的见解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

npj Biofilms and Microbiomes Immunology and Microbiology-Microbiology

CiteScore

12.10

自引率

3.30%

发文量

审稿时长

9 weeks

期刊介绍： npj Biofilms and Microbiomes is a comprehensive platform that promotes research on biofilms and microbiomes across various scientific disciplines. The journal facilitates cross-disciplinary discussions to enhance our understanding of the biology, ecology, and communal functions of biofilms, populations, and communities. It also focuses on applications in the medical, environmental, and engineering domains. The scope of the journal encompasses all aspects of the field, ranging from cell-cell communication and single cell interactions to the microbiomes of humans, animals, plants, and natural and built environments. The journal also welcomes research on the virome, phageome, mycome, and fungome. It publishes both applied science and theoretical work. As an open access and interdisciplinary journal, its primary goal is to publish significant scientific advancements in microbial biofilms and microbiomes. The journal enables discussions that span multiple disciplines and contributes to our understanding of the social behavior of microbial biofilm populations and communities, and their impact on life, human health, and the environment.