Advanced Thermoactive Nanomaterials for Thermomedical Tissue Regeneration: Opportunities and Challenges.

IF 10.7 2区材料科学 Q1 CHEMISTRY, PHYSICAL

Small Methods Pub Date : 2024-11-26 DOI:10.1002/smtd.202400510

Ting Li, Long Zhang, Xiaoyan Qu, Bo Lei

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引用次数: 0

Abstract

Nanomaterials usually possess remarkable properties, including excellent biocompatibility, unique physical and chemical characteristics, and bionic attributes, which make them highly promising for applications in tissue regeneration. Thermal therapy has emerged as a versatile approach for wound healing, nerve repair, bone regeneration, tumor therapy, and antibacterial tissue regeneration. By combining nanomaterials with thermal therapy, multifunctional nanomaterials with thermogenic effects and tissue regeneration capabilities can be engineered to achieve enhanced therapeutic outcomes. This study provides a comprehensive review of the effects of thermal stimulation on cellular and tissue regeneration. Furthermore, it highlights the applications of photothermal, magnetothermal, and electrothermal nanomaterials, and thermally responsive drug delivery systems in tissue engineering. In Addition, the bioactivities and biocompatibilities of several representative thermal nanomaterials are discussed. Finally, the challenges facing thermal nanomaterials are outlined, and future prospects in the field are presented with the aim of offering new opportunities and avenues for the utilization of thermal nanomaterials in tissue regeneration.

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用于热医学组织再生的先进热活性纳米材料：机遇与挑战。

纳米材料通常具有卓越的特性，包括极佳的生物相容性、独特的物理和化学特性以及仿生属性，这些特性使其在组织再生方面极具应用前景。热疗已成为伤口愈合、神经修复、骨再生、肿瘤治疗和抗菌组织再生的多功能方法。通过将纳米材料与热疗法相结合，可以设计出具有致热效应和组织再生能力的多功能纳米材料，从而达到更好的治疗效果。本研究全面综述了热刺激对细胞和组织再生的影响。此外，它还重点介绍了光热、磁热和电热纳米材料以及热响应给药系统在组织工程中的应用。此外，还讨论了几种具有代表性的热纳米材料的生物活性和生物相容性。最后，概述了热纳米材料面临的挑战，并介绍了该领域的未来前景，旨在为热纳米材料在组织再生中的应用提供新的机遇和途径。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Small Methods Materials Science-General Materials Science

CiteScore

17.40

自引率

1.60%

发文量

347

期刊介绍： Small Methods is a multidisciplinary journal that publishes groundbreaking research on methods relevant to nano- and microscale research. It welcomes contributions from the fields of materials science, biomedical science, chemistry, and physics, showcasing the latest advancements in experimental techniques. With a notable 2022 Impact Factor of 12.4 (Journal Citation Reports, Clarivate Analytics, 2023), Small Methods is recognized for its significant impact on the scientific community. The online ISSN for Small Methods is 2366-9608.