Recent Strategies and Advances in Hydrogel-Based Delivery Platforms for Bone Regeneration

IF 26.6 1区材料科学 Q1 Engineering

Nano-Micro Letters Pub Date : 2024-11-27 DOI:10.1007/s40820-024-01557-4

Xiao Wang, Jia Zeng, Donglin Gan, Kun Ling, Mingfang He, Jianshu Li, Yongping Lu

引用次数: 0

Abstract

Highlights

Recent advances in the combined delivery platform that integrate nano-/microscale carriers and with 3D hydrogel network for bone regeneration are summarized.
The strategies for bioactive molecules delivery involving nanoparticles, nanosheets, and microspheres, along with extra stimuli such as near-infrared light, temperature changes, ultrasonication, and inflammatory conditions, are introduced.
The prospects and challenges for the clinical translation and the development of nano-/microscale incorporated hydrogel-based delivery platform are discussed.

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基于水凝胶的骨再生传输平台的最新战略和进展

亮点概述整合纳米/微米级载体和三维水凝胶网络的联合递送平台在骨再生方面的最新进展。介绍了涉及纳米颗粒、纳米片和微球的生物活性分子递送策略，以及额外刺激（如近红外线、温度变化、超声波和炎症条件）。此外，还讨论了基于纳米/微尺度水凝胶的递送平台的临床转化和发展前景与挑战。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nano-Micro Letters NANOSCIENCE & NANOTECHNOLOGY-MATERIALS SCIENCE, MULTIDISCIPLINARY

CiteScore

32.60

自引率

4.90%

发文量

981

审稿时长

1.1 months

期刊介绍： Nano-Micro Letters is a peer-reviewed, international, interdisciplinary, and open-access journal published under the SpringerOpen brand. Nano-Micro Letters focuses on the science, experiments, engineering, technologies, and applications of nano- or microscale structures and systems in various fields such as physics, chemistry, biology, material science, and pharmacy.It also explores the expanding interfaces between these fields. Nano-Micro Letters particularly emphasizes the bottom-up approach in the length scale from nano to micro. This approach is crucial for achieving industrial applications in nanotechnology, as it involves the assembly, modification, and control of nanostructures on a microscale.