Synthesis and applications of luminescent metal organic frameworks (MOFs) for sensing dipicolinic acid in biological and water samples: a review

IF 4.6 3区材料科学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Nanoscale Advances Pub Date : 2024-11-21 DOI:10.1039/D4NA00652F

Kawan F. Kayani, Omer B. A. Shatery, Sewara J. Mohammed, Harez Rashid Ahmed, Rebaz F. Hamarawf and Muhammad S. Mustafa

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Abstract

The detection of trace quantities of 2,6-dipicolinic acid (DPA) in real-world samples is crucial for early disease diagnosis and routine health monitoring. Metal–organic frameworks (MOFs), recognized for their diverse structural architectures, have emerged as advanced multifunctional hybrid materials. One of the most notable properties of MOFs is their luminescence (L), which can arise from structural ligands, guest molecules, and emissive metal ions. Luminescent MOFs have shown significant promise as platforms for sensor design. This review highlights the application of luminescent MOFs in the detection of DPA in biological and aqueous environments. It provides a comprehensive discussion of the various detection strategies employed in luminescent MOF-based DPA sensors. Additionally, it explores the origins of L in MOFs, their synthesis, and the mechanisms underlying their sensing capabilities. The article also addresses key challenges and limitations in this field, offering practical insights for the development of efficient luminescent MOFs for DPA detection.

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用于传感生物和水样中二砒啶酸的发光金属有机框架 (MOF) 的合成与应用：综述。

检测真实世界样本中的痕量 2,6-二吲哚啉酸 (DPA) 对于早期疾病诊断和常规健康监测至关重要。金属有机框架（MOFs）因其多样化的结构体系而被公认为先进的多功能混合材料。MOFs 最显著的特性之一是发光（L），它可以由结构配体、客体分子和发光金属离子产生。发光 MOFs 已显示出作为传感器设计平台的巨大前景。本综述重点介绍了发光 MOFs 在生物和水环境中 DPA 检测中的应用。它全面讨论了基于发光 MOF 的 DPA 传感器所采用的各种检测策略。此外，文章还探讨了 MOF 中发光的起源、合成及其传感功能的基本机制。文章还探讨了该领域的主要挑战和局限性，为开发用于 DPA 检测的高效发光 MOFs 提供了实用的见解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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