Analysis of tire wear-derived toxic organic substances and associated toxicological implications by mass spectrometry: Recent advances

IF 11.8 1区化学 Q1 CHEMISTRY, ANALYTICAL

Trends in Analytical Chemistry Pub Date : 2024-11-18 DOI:10.1016/j.trac.2024.118059

Congcong Pei , Shijiao Hou , Zifang Peng , Xu Zhang , Dan Yin , Wenfen Zhang , Yanhao Zhang , Zongwei Cai , Shusheng Zhang

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Abstract

Tire wear-derived toxic organic substances (TWTOSs), as broadly distributed and poisonous contaminants, have threatened the safety of the environment, food, and organisms. Accurate, sensitive, and rapid detection of TWTOSs is essential for understanding their occurrence, environmental fate, and biotoxicities. Mass spectrometry (MS) has been increasingly employed for identification, quantification, and toxicity tracking of emerging pollutants in terms of high sensitivity/throughput and easy operation. Herein, we reviewed the recent advances of MS technology for detecting TWTOSs (e.g., cyclic amines and benzotriazoles/benzothiazoles) in the ecosystem and food/biological samples, and assessing the toxicological implications of TWTOSs on the organism. A comprehensive update on the MS-based detection of TWTOSs and the exposure risks’ evaluation will be provided in this review, highlighting the necessity of innovation of analytical technology for environmental and public health safety.

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利用质谱法分析轮胎磨损产生的有毒有机物质及其相关毒理学影响：最新进展

轮胎磨损产生的有毒有机物质（TWTOSs）是一种广泛分布的有毒污染物，已威胁到环境、食物和生物体的安全。准确、灵敏、快速地检测 TWTOSs 对了解其发生、环境归宿和生物毒性至关重要。质谱（MS）具有高灵敏度/高通量和操作简便的特点，越来越多地被用于新出现污染物的鉴定、定量和毒性跟踪。在此，我们回顾了质谱技术在检测生态系统和食物/生物样本中的 TWTOSs（如环胺和苯并三唑/苯并噻唑）以及评估 TWTOSs 对生物体的毒理学影响方面的最新进展。本综述将全面介绍基于质谱的 TWTOSs 检测和暴露风险评估的最新进展，并强调为确保环境和公共健康安全而创新分析技术的必要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Trends in Analytical Chemistry 化学-分析化学

CiteScore

20.00

自引率

4.60%

发文量

257

审稿时长

3.4 months

期刊介绍： TrAC publishes succinct and critical overviews of recent advancements in analytical chemistry, designed to assist analytical chemists and other users of analytical techniques. These reviews offer excellent, up-to-date, and timely coverage of various topics within analytical chemistry. Encompassing areas such as analytical instrumentation, biomedical analysis, biomolecular analysis, biosensors, chemical analysis, chemometrics, clinical chemistry, drug discovery, environmental analysis and monitoring, food analysis, forensic science, laboratory automation, materials science, metabolomics, pesticide-residue analysis, pharmaceutical analysis, proteomics, surface science, and water analysis and monitoring, these critical reviews provide comprehensive insights for practitioners in the field.